t-Boc-N-amido-PEG2-acid

Product Name: t-Boc-N-amido-PEG2-acid
CAS No.: 1365655-91-9
Chemical Name: t-Boc-N-amido-PEG2-acid
Synonyms: 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid;t-boc-N-amido-PEG2-propionic acid;Boc-NH-PEG2-acid;Boc-NH-PEG2-COOH;BocNH-PEG2-C2-COOH;Boc-N-amido-PEG2-acid;N-Boc-amino-PEG3-acid;t-Boc-N-amido-PEG2-acid;T-BOC-NH-AMIDO-PEG2-COOH;BOC-AMINO-PEG2-PROPANOIC ACID
CBNumber: CB33062664
Molecular Formula: C12H23NO6
Formula Weight: 277.31
MOL File: 1365655-91-9.mol

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t-Boc-N-amido-PEG2-acid Property

Boiling point:: 429.9±35.0 °C(Predicted)
Density: 1.125±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: B601895
Product name: T-Boc-N-Amido-peg2-acid
Packaging: 100mg
Price: $90
Updated: 2021/12/16

TRC

Product number: B601895
Product name: T-Boc-N-Amido-peg2-acid
Packaging: 500mg
Price: $350
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4156-1-0Q
Product name: t-Boc-N-amido-PEG2-acid
Packaging: 1g
Price: $352
Updated: 2021/12/16

Matrix Scientific

Product number: 179890
Product name: N-Boc-3-[2-(2-aminoethoxy)ethoxy]propionic acid
Purity: 95%
Packaging: 1g
Price: $578
Updated: 2021/12/16

AK Scientific

Product number: 7229AJ
Product name: N-Boc-3-[2-(2-aminoethoxy)ethoxy]propionicacid
Packaging: 5g
Price: $847
Updated: 2021/12/16

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t-Boc-N-amido-PEG2-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG2-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG2-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

IC 50

PEGs; Alkyl/ether

References

[1] Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis TargetingChimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable TumorRegression. J Med Chem. 2019 Jan 24;62(2):448-466. DOI:10.1021/acs.jmedchem.8b00909

t-Boc-N-amido-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG2-acid Suppliers

China 100 India 1 United Kingdom 1 United States 8 Global 110

Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 021-50929289 18616309303
Fax: -
Email: sales@ypptech.com.cn
Country: China
ProdList: 366
Advantage: 58

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Biomatrik (Jiaxing) Inc.

Tel: 573-573-82623377 18967387295
Fax: +86 (573) 8262-3317
Email: sales@biomatrik.cn
Country: China
ProdList: 70
Advantage: 61

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11654
Advantage: 64

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 021-51613915-820 13611835272
Fax: 021 51613951
Email: mmwang@sunwaypharm.cn
Country: China
ProdList: 9732
Advantage: 57

Chengdu Pukang Biotechnology Co., Ltd

Tel: +86-028-82550498 +86-19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 489
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 1316706386
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 282
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41457
Advantage: 60

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View Lastest Price from t-Boc-N-amido-PEG2-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: t-Boc-N-amido-PEG2-acid 1365655-91-9
Price: US $0.00/g
Min. Order: 25g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-25

Career Henan Chemical Co

Product: t-Boc-N-amido-PEG2-acid 1365655-91-9
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-09

1365655-91-9, t-Boc-N-amido-PEG2-acidRelated Search:

t-Boc-N-amido-PEG1-acid 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- t-boc-N-amido-PEG4-NHS ester t-Boc-N-amido-PEG8-acid t-Boc-N-amido-PEG15-acid t-Boc-N-amido-PEG10-acid O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid t-boc-N-amido-PEG14-amine O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG17-acid t-boc-N-amido-PEG13-amine t-Boc-N-amido-PEG14-acid t-boc-N-amido-PEG16-amine t-Boc-N-amido-PEG11-acid

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid

BOC-AMINO-PEG2-PROPANOIC ACID

t-Boc-N-amido-PEG2-acid

N-Boc-3-[2-(2-aminoethoxy)ethoxy]propionic Acid

Boc-N-amido-PEG2-acid

3-[2-(2-([(tert-Butoxy)carbonyl]amino)ethoxy)ethoxy]propanoic acid

t-boc-N-amido-PEG2-propionic acid

Boc-NH-PEG2-COOH

T-BOC-NH-AMIDO-PEG2-COOH

4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-

Boc-NH-PEG2-acid

BocNH-PEG2-CH2CH2COOH/4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-

N-Boc-amino-PEG3-acid

BocNH-PEG2-C2-COOH

1365655-91-9

ADCs Linkers

PROTAC Linker

PROTAC

peg