t-Boc-N-amido-PEG2-acid

Product Name: t-Boc-N-amido-PEG2-acid
CAS No.: 1365655-91-9
Chemical Name: t-Boc-N-amido-PEG2-acid
Synonyms: 2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid;t-boc-N-amido-PEG2-propionic acid;Boc-NH-PEG2-acid;Boc-NH-PEG2-COOH;BocNH-PEG2-C2-COOH;Boc-N-amido-PEG2-acid;N-Boc-amino-PEG3-acid;t-Boc-N-amido-PEG2-acid;T-BOC-NH-AMIDO-PEG2-COOH;BOC-AMINO-PEG2-PROPANOIC ACID
CBNumber: CB33062664
Molecular Formula: C12H23NO6
Formula Weight: 277.31
MOL File: 1365655-91-9.mol

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t-Boc-N-amido-PEG2-acid Property

Boiling point:: 429.9±35.0 °C(Predicted)
Density: 1.125±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: Liquid
pka: 4.28±0.10(Predicted)
color: Colorless to light yellow
InChI: InChI=1S/C12H23NO6/c1-12(2,3)19-11(16)13-5-7-18-9-8-17-6-4-10(14)15/h4-9H2,1-3H3,(H,13,16)(H,14,15)
InChIKey: OZMXZVCAXAQCHJ-UHFFFAOYSA-N
SMILES: C(O)(=O)CCOCCOCCNC(=O)OC(C)(C)C

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D5825
Product name: Boc-NH-PEG2-acid
Packaging: 250MG
Price: $176
Updated: 2025/07/31

TRC

Product number: B601895
Product name: T-Boc-N-Amido-peg2-acid
Packaging: 100mg
Price: $90
Updated: 2021/12/16

TRC

Product number: B601895
Product name: T-Boc-N-Amido-peg2-acid
Packaging: 500mg
Price: $350
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4156-1-0Q
Product name: t-Boc-N-amido-PEG2-acid
Packaging: 1g
Price: $352
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4156-1-0Q
Product name: t-Boc-N-amido-PEG2-acid
Packaging: 100mg
Price: $72
Updated: 2021/12/16

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t-Boc-N-amido-PEG2-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG2-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG2-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

IC 50

PEGs; Alkyl/ether

References

[1] Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis TargetingChimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable TumorRegression. J Med Chem. 2019 Jan 24;62(2):448-466. DOI:10.1021/acs.jmedchem.8b00909

t-Boc-N-amido-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG2-acid Suppliers

China 108 India 1 United Kingdom 1 United States 8 Global 118

Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 021-50929289 18616309303
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Email: sales@ypptech.com.cn
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CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD

Tel: 17882285575
Email: 1276966012@qq.com
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Biomatrik (Jiaxing) Inc.

Tel: 573-573-82623377 18967387295
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Email: sales@biomatrik.cn
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Accela ChemBio Co.,Ltd.

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Email: sales@accelachem.com
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Chengdu Pukang Biotechnology Co., Ltd

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T&W GROUP

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Hygeia (Chengdu) pharmaceutical technique Co., Ltd

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Bide Pharmatech Ltd.

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Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
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View Lastest Price from t-Boc-N-amido-PEG2-acid manufacturers

LAURENT

Product: BocNH-PEG2-CH2CH2COOH 1365655-91-9
Price: US $34.13/g
Min. Order: 10g
Purity: 98%
Supply Ability: 500kg
Release date: 2025-11-20

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid 1365655-91-9
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: t-Boc-N-amido-PEG2-acid 1365655-91-9
Price: US $0.00/g
Min. Order: 25g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-25

1365655-91-9, t-Boc-N-amido-PEG2-acidRelated Search:

t-Boc-N-amido-PEG1-acid 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- t-boc-N-amido-PEG4-NHS ester t-Boc-N-amido-PEG8-acid t-Boc-N-amido-PEG15-acid t-Boc-N-amido-PEG10-acid O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid t-boc-N-amido-PEG14-amine O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG17-acid t-boc-N-amido-PEG13-amine t-Boc-N-amido-PEG14-acid t-boc-N-amido-PEG16-amine t-Boc-N-amido-PEG11-acid

2,2-Dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oic acid

BOC-AMINO-PEG2-PROPANOIC ACID

t-Boc-N-amido-PEG2-acid

N-Boc-3-[2-(2-aminoethoxy)ethoxy]propionic Acid

Boc-N-amido-PEG2-acid

3-[2-(2-([(tert-Butoxy)carbonyl]amino)ethoxy)ethoxy]propanoic acid

t-boc-N-amido-PEG2-propionic acid

Boc-NH-PEG2-COOH

T-BOC-NH-AMIDO-PEG2-COOH

4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-

Boc-NH-PEG2-acid

BocNH-PEG2-CH2CH2COOH/4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-

N-Boc-amino-PEG3-acid

BocNH-PEG2-C2-COOH

1365655-91-9

ADCs Linkers

PROTAC Linker

PROTAC

peg