ChemicalBook > CAS DataBase List > 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-

Product Name
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
CAS No.
108466-89-3
Chemical Name
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
Synonyms
2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid;Boc-AEEA-OH;2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid;Boc-O 2 Oc-OH;2-diMethyl-4-oxo-;BocNH-PEG2-CH2COOH;NHBoc-PEG2-CH2COOH;Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-Amido-PEG2-CH2COOH
CBNumber
CB02639228
Molecular Formula
C11H21NO6
Formula Weight
263.29
MOL File
108466-89-3.mol
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3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Property

Boiling point:
425.7±30.0 °C(Predicted)
Density 
1.145±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
3.40±0.10(Predicted)
form 
liquid
color 
Yellow
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Safety

HS Code 
2918999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
901577
Product name
t-Boc-N-amido-PEG2-CH2CO2H
Purity
≥95%
Packaging
50MG
Price
$34.4
Updated
2023/06/20
TRC
Product number
B694050
Product name
8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoicAcid
Packaging
2.5g
Price
$1260
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG8080
Product name
Boc-O2Oc
Packaging
25g
Price
$1350
Updated
2021/12/16
ChemPep
Product number
280209
Product name
Boc-AEEA
Packaging
5g
Price
$250
Updated
2021/12/16
Apolloscientific
Product number
BIPG1825
Product name
t-Boc-N-amido-PEG2-CH2CO2H
Packaging
5g
Price
$540
Updated
2021/12/16
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3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG2-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.

3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Preparation Products And Raw materials

Raw materials

Preparation Products

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3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Suppliers

China 144 India 3 United Kingdom 1 United States 9 Global 157
Ji'nan tengbang pharmaceutical science and Technology Co., Ltd.
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0531-88769236 15688889648
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2685550793@qq.com
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China
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0556-05565032870 13770767175
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liangzhi.xu@nuoquanpharm.com
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China
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China
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Shanghai Huici Pharmaceutical Technology Co., LTD
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Shanghai Haohong Pharmaceutical Co., Ltd.
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Nanjing Quantong Pharmaceutical Technology Co., Ltd
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PharmaBlock Sciences (Nanjing),Inc.
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sales@pharmablock.com
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
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Beijing Isomersyn Technology CO;LTD
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010-82954736 13391601435
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sales@isomersyn.com
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China
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View Lastest Price from 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- manufacturers

Career Henan Chemical Co
Product
2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid 108466-89-3
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-25

108466-89-3, 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-Related Search:

N-Boc-PEG6-alcohol N-BOC-AMINOEHTOXY-ETHOXY-ETHOXY-ETHANOL O-(2-AMinoethyl)-O'-[2-(Boc-aMino)ethyl]tetraethylene Glycol 5,8,11-Trioxa-2-azatridecanoic,13-amino,1,1-dimethylethyl ester O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 Carbamic acid, [2-(2-aminoethoxy)ethyl]-, 1,1-dimethylethyl ester (9CI) O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Z-8-aMino-3,6-dioxaoctanoic acid t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG2-acid 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID t-Boc-N-amido-PEG1-acid

  • Boc-N-amido-PEG2-CH2CO2H
  • t-boc-N-amido-PEG2-acetic acid
  • 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
  • 8-tert-butyloxycarbonylaMino-3,6-dioxaoctanoic acid
  • 2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid
  • 2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid
  • t-Boc-N-amido-PEG2-CH2CO2H
  • BocNH-PEG2-CH2COOH
  • T-BOC-NH-AMIDO-PEG2-CH2CO2H
  • 2-[2-[2-(Boc-amino)ethoxy]ethoxy]acetic Acid
  • Boc-AEEA-OH
  • 2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]acetic acid
  • 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo-
  • 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- USP/EP/BP
  • 11-Trioxa-5-azatridecan-13-oic acid
  • 2-diMethyl-4-oxo-
  • NHBoc-PEG2-CH2COOH
  • t-Boc-N-Amido-PEG2-CH2COOH
  • N-Boc-8-amino-3,6-dioxaoctanoic acid
  • Boc-O 2 Oc-OH
  • 2-[2-(2-([(tert-butoxy)carbonylaminoJethoxy)ethoxylacetic acid
  • 2,2-dimethyl-4,13-dioxo-3,8,11-trioxa-5-azatetradecan-14-oic acid
  • 108466-89-3
  • 137978-97-5
  • peg