Boc-9-AMino-4,7-Dioxanonanoic acid
- Product Name
- Boc-9-AMino-4,7-Dioxanonanoic acid
- CAS No.
- 1347750-75-7
- Chemical Name
- Boc-9-AMino-4,7-Dioxanonanoic acid
- Synonyms
- BocNH-PEG3-C2-COOH;Boc-N-amido-PEG3-acid;Boc-PEG3- CH2 CH2COOH;Boc-NH-PEG3-CH2CH2COOH;t-Boc-N-amido-PEG3-acid;T-BOC-NH-AMIDO-PEG3-COOH;t-boc-N-amido-PEG3-propionic acid;Boc-9-AMino-4,7-Dioxanonanoic acid;(Boc-amino)-PEG3-C2-Carboxylic Acid;(Boc-amino)-PEG3-C?-Carboxylic Acid
- CBNumber
- CB52546837
- Molecular Formula
- C14H27NO7
- Formula Weight
- 321.37
- MOL File
- 1347750-75-7.mol
Boc-9-AMino-4,7-Dioxanonanoic acid Property
- Boiling point:
- 471.1±40.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO (Sparingly), Methanol(Sparingly)
- pka
- 4.28±0.10(Predicted)
- form
- Oil
- color
- Colourless
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B6093
- Product name
- (Boc-amino)-PEG3-C2-Carboxylic Acid
- Packaging
- 250MG
- Price
- $153
- Updated
- 2024/03/01
- Product number
- B603010
- Product name
- t-Boc-N-amido-PEG3-acid
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- B603010
- Product name
- t-Boc-N-amido-PEG3-acid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B603010
- Product name
- t-Boc-N-amido-PEG3-acid
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 466731
- Product name
- t-Boc-N-amido-PEG3-acid
- Packaging
- 25mg
- Price
- $305
- Updated
- 2021/12/16
Boc-9-AMino-4,7-Dioxanonanoic acid Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG3-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-N-amido-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-9-AMino-4,7-Dioxanonanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Boc-9-AMino-4,7-Dioxanonanoic acid Suppliers
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- 025-66110311 13155353615
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- China
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View Lastest Price from Boc-9-AMino-4,7-Dioxanonanoic acid manufacturers
- Product
- t-Boc-N-amido-PEG3-acid 1347750-75-7
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- Boc-9-AMino-4,7-Dioxanonanoic acid 1347750-75-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31