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t-Boc-N-amido-PEG8-acid

Product Name
t-Boc-N-amido-PEG8-acid
CAS No.
1334169-93-5
Chemical Name
t-Boc-N-amido-PEG8-acid
Synonyms
Boc-NH-PEG8-acid;BocNH-PEG8-C2-COOH;Boc-N-amido-PEG8-acid;t-Boc-N-amido-PEG9-acid;t-Boc-N-amido-PEG8-acid;T-BOC-NH-AMIDO-PEG8-COOH;Boc-NH-PEG8-Propionic Acid;t-boc-N-amido-dPEG??-acid (QBD-10760);t-Boc-N-amido-PEG8-COOH,Boc-N-amido-PEG8-acid;1-(tert-Butyl) 5,8,11,14,17,20,23,26-octaoxa-2-azanonacosanedioate
CBNumber
CB83062669
Molecular Formula
C24H47NO12
Formula Weight
541.63
MOL File
1334169-93-5.mol
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t-Boc-N-amido-PEG8-acid Property

Boiling point:
627.6±55.0 °C(Predicted)
Density 
1.122±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
4.28±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C24H47NO12/c1-24(2,3)37-23(28)25-5-7-30-9-11-32-13-15-34-17-19-36-21-20-35-18-16-33-14-12-31-10-8-29-6-4-22(26)27/h4-21H2,1-3H3,(H,25,28)(H,26,27)
InChIKey
XYVCCDSFTREKQJ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B601905
Product name
T-Boc-N-Amido-PEG8-Acid
Packaging
100mg
Price
$265
Updated
2021/12/16
Iris Biotech GmbH
Product number
PEG2410
Product name
Boc-NH-PEG(8)-COOH
Packaging
100mg
Price
$351
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002548
Product name
TERT-BOC-PEG8-ACID
Purity
95.00%
Packaging
100MG
Price
$354.9
Updated
2021/12/16
dPEG
Product number
10760
Product name
t-boc-N-amido-dPEG®₈-acid
Packaging
1000mg
Price
$500
Updated
2021/12/16
Activate Scientific
Product number
AS103911
Product name
BocNH-PEG8-CH2CH2COOH
Purity
95+%
Packaging
1g
Price
$693
Updated
2021/12/16
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t-Boc-N-amido-PEG8-acid Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG8-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-amido-PEG8-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG8-acid Suppliers

China 88 India 1 United Kingdom 1 United States 4 Global 94
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
13892832556
Email
2440688701@qq.com
Country
China
ProdList
1994
Advantage
58
Shanghai Yanfen Biochemical Technology Co.,LTD
Tel
17721070236 15002190549;
Email
yanfen2023@126.com
Country
China
ProdList
1837
Advantage
58
CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD
Tel
17882285575
Email
1276966012@qq.com
Country
China
ProdList
390
Advantage
58
Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
970
Advantage
59
ChemPep, Inc.
Tel
+1 (888) 615-9178 / (561) 791-8787
Fax
+1 (561) 791-8728
Email
service@chempep.com
Country
United States
ProdList
2138
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
+86-028-82550498 +86-19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
497
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58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
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View Lastest Price from t-Boc-N-amido-PEG8-acid manufacturers

LAURENT
Product
BocNH-PEG8-CH2CH2COOH 1334169-93-5
Price
US $386.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-15
XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2,2-dimethyl-4-oxo-3,8,11,14,17,20,23,26,29-nonaoxa-5-azadotriacontan-32-oic acid 1334169-93-5
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Boc-NH-PEG8-CH2CH2COOH 1334169-93-5
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-06

1334169-93-5, t-Boc-N-amido-PEG8-acidRelated Search:

BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID t-Boc-N-amido-PEG15-acid t-Boc-N-amido-PEG10-acid O-[2-(Boc-amino)ethyl]-Oμ-(2-carboxyethyl)polyethylene glycol 3,000 O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL BOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID t-Boc-N-amido-PEG5-acid Boc-9-AMino-4,7-Dioxanonanoic acid t-boc-N-amido-PEG14-amine O-(2-AMINOETHYL)-O'-(2-(BOC-AMINO)ETHYL) t-Boc-N-amido-PEG17-acid t-boc-N-amido-PEG13-amine t-Boc-N-amido-PEG2-acid t-Boc-N-amido-PEG14-acid t-boc-N-amido-PEG16-amine t-Boc-N-amido-PEG11-acid 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester

  • 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(1,1-dimethylethyl) ester
  • t-Boc-N-amido-PEG8-acid
  • t-Boc-N-amido-PEG9-acid
  • Boc-N-amido-PEG8-acid
  • T-BOC-NH-AMIDO-PEG8-COOH
  • t-Boc-N-amido-PEG8-COOH,Boc-N-amido-PEG8-acid
  • Boc-NH-PEG8-acid
  • 2,2-Dimethyl-4-oxo-3,8,11,14,17,20,23,26,29-nonaoxa-5-azadotriacontan-32-oic acid
  • BocNH-PEG8-C2-COOH
  • 1-(1,1-Dimethylethyl) 5,8,11,14,17,20,23,26-octaoxa-2-azanonacosanedioate
  • Boc NH PEG8 CH2CH2COOH,inhibit,Inhibitor,PROTAC Linkers,Boc-NH-PEG-8-CH2CH2COOH,BocNHPEG8CH2CH2COOH
  • BocNH-PEG8-CH2CH2COOH/5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid, 1-(1,1-dimethylethyl) ester
  • 1-(tert-Butyl) 5,8,11,14,17,20,23,26-octaoxa-2-azanonacosanedioate
  • 3-[2-[2-[2-[2-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
  • t-boc-N-amido-dPEG??-acid (QBD-10760)
  • alpha-tert-Butyloxycarbonylamino-omega-carboxy octa(ethylene glycol)
  • 3-[2-[2-[2-[2-[2-[2-[2-[2-(tert-butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid - [B82351]
  • Boc-NH-PEG8-Propionic Acid
  • 1334169-93-5
  • C24H47NO12
  • peg