3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
- Product Name
- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
- CAS No.
- 108466-89-3
- Chemical Name
- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
- Synonyms
- 2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid;Boc-AEEA-OH;2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid;Boc-O 2 Oc-OH;2-diMethyl-4-oxo-;BocNH-PEG2-CH2COOH;NHBoc-PEG2-CH2COOH;Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-amido-PEG2-CH2CO2H;t-Boc-N-Amido-PEG2-CH2COOH
- CBNumber
- CB02639228
- Molecular Formula
- C11H21NO6
- Formula Weight
- 263.29
- MOL File
- 108466-89-3.mol
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Property
- Boiling point:
- 425.7±30.0 °C(Predicted)
- Density
- 1.145±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 3.40±0.10(Predicted)
- form
- liquid
- color
- Yellow
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 901577
- Product name
- t-Boc-N-amido-PEG2-CH2CO2H
- Purity
- ≥95%
- Packaging
- 50MG
- Price
- $34.4
- Updated
- 2023/06/20
- Product number
- B694050
- Product name
- 8-tert-Butyloxycarbonylamino-3,6-dioxaoctanoicAcid
- Packaging
- 2.5g
- Price
- $1260
- Updated
- 2021/12/16
- Product number
- PEG8080
- Product name
- Boc-O2Oc
- Packaging
- 25g
- Price
- $1350
- Updated
- 2021/12/16
- Product number
- 280209
- Product name
- Boc-AEEA
- Packaging
- 5g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- BIPG1825
- Product name
- t-Boc-N-amido-PEG2-CH2CO2H
- Packaging
- 5g
- Price
- $540
- Updated
- 2021/12/16
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG2-CH2CO2H is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Preparation Products And Raw materials
Raw materials
Preparation Products
3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- Suppliers
View Lastest Price from 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- manufacturers
- Product
- 2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]acetic acid 108466-89-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-25