t-boc-N-amido-PEG4-NHS ester
- Product Name
- t-boc-N-amido-PEG4-NHS ester
- CAS No.
- 859230-20-9
- Chemical Name
- t-boc-N-amido-PEG4-NHS ester
- Synonyms
- Boc-NH-PEG4-SPA;CAS_859230-20-9;BocNH-P5-NHS ester;Boc-NH-PEG4-NHS ester;BocNH-PEG4-CH2CH2COONHS;t-boc-N-amido-PEG4-NHS ester;BocNH-PEG4-CH2CH2COONHS ester;2,5-DIOXOPYRROLIDIN-1-YL 2,2-DIMETHYL-4-OXO-3,8,11,14,17-PENTAOXA-5-AZAICOSAN-20-OATE;5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(1,1-dimethylethyl) 17-(2,5-dioxo-1-pyrrolidinyl) ester;BocNH-PEG4-CH2CH2COONHS/5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(1,1-dimethylethyl) 17-(2,5-dioxo-1-pyrrolidinyl) ester
- CBNumber
- CB03133857
- Molecular Formula
- C20H34N2O10
- Formula Weight
- 462.49
- MOL File
- 859230-20-9.mol
t-boc-N-amido-PEG4-NHS ester Property
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Viscous Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23472
- Product name
- t-Boc-N-amido-PEG4-NHSester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- AS107875
- Product name
- BocNH-PEG4-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $711
- Updated
- 2021/12/16
- Product number
- B-1466
- Product name
- BocNH-PEG4-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- B-1466
- Product name
- BocNH-PEG4-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $330
- Updated
- 2021/12/16
t-boc-N-amido-PEG4-NHS ester Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG4-NHS ester is a PEG linker containing a Boc-protected amine group and an NHS ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The protected amine can be deprotected by acidic conditions.
Uses
Boc-NH-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-boc-N-amido-PEG4-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
t-boc-N-amido-PEG4-NHS ester Suppliers
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View Lastest Price from t-boc-N-amido-PEG4-NHS ester manufacturers
- Product
- BocNH-PEG4-CH2CH2COONHS ester 859230-20-9
- Price
- US $426.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-19
- Product
- t-Boc-N-amido-PEG4-NHS ester 859230-20-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25