Boc-Aminooxy-PEG3-acid
- Product Name
- Boc-Aminooxy-PEG3-acid
- CAS No.
- 1835759-82-4
- Chemical Name
- Boc-Aminooxy-PEG3-acid
- Synonyms
- BocHNO-PEG3-CH2CH2COOH;Boc-Aminooxy-PEG3-acid;N-Boc-Aminooxy-PEG3-acid;t-Boc-Aminooxy-PEG3-acid;t-Boc-Aminooxy-PEG3-acid t-Boc-;2,2-Dimethyl-4-oxo-3,6,9,12,15-pentaoxa-5-azaoctadecan-18-oic acid;1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10-tetraoxatridecan-13-oic acid;3,6,9,12-Tetraoxa-2-azapentadecanedioic acid, 1-(1,1-dimethylethyl) ester
- CBNumber
- CB83162901
- Molecular Formula
- C14H27NO8
- Formula Weight
- 337.37
- MOL File
- 1835759-82-4.mol
Boc-Aminooxy-PEG3-acid Property
- Density
- 1.155±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DMF, DCM
- pka
- 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-22966
- Product name
- t-Boc-Aminooxy-PEG3-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $780
- Updated
- 2021/12/16
Boc-Aminooxy-PEG3-acid Chemical Properties,Usage,Production
Description
t-Boc-Aminooxy-PEG3-acid is a PEG linker containing a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions.
Uses
Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Boc-Aminooxy-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Boc-Aminooxy-PEG3-acid Suppliers
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28772
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32467
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 1995
- Advantage
- 58
- Tel
- 15268198094
- sales@torreybio.com
- Country
- China
- ProdList
- 3943
- Advantage
- 58
- Tel
- 13303867194
- 3001317055@qq.com
- Country
- China
- ProdList
- 9800
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
View Lastest Price from Boc-Aminooxy-PEG3-acid manufacturers
- Product
- t-Boc-Aminooxy-PEG3-acid 1835759-82-4
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22