Boc-Aminooxy-PEG3-acid

Product Name: Boc-Aminooxy-PEG3-acid
CAS No.: 1835759-82-4
Chemical Name: Boc-Aminooxy-PEG3-acid
Synonyms: BocHNO-PEG3-CH2CH2COOH;Boc-Aminooxy-PEG3-acid;N-Boc-Aminooxy-PEG3-acid;t-Boc-Aminooxy-PEG3-acid;t-Boc-Aminooxy-PEG3-acid t-Boc-;2,2-Dimethyl-4-oxo-3,6,9,12,15-pentaoxa-5-azaoctadecan-18-oic acid;1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10-tetraoxatridecan-13-oic acid;3,6,9,12-Tetraoxa-2-azapentadecanedioic acid, 1-(1,1-dimethylethyl) ester
CBNumber: CB83162901
Molecular Formula: C14H27NO8
Formula Weight: 337.37
MOL File: 1835759-82-4.mol

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Boc-Aminooxy-PEG3-acid Property

Density: 1.155±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DMF, DCM
pka: 4.28±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22966
Product name: t-Boc-Aminooxy-PEG3-acid
Purity: 98%
Packaging: 250mg
Price: $780
Updated: 2021/12/16

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Boc-Aminooxy-PEG3-acid Chemical Properties,Usage,Production

Description

t-Boc-Aminooxy-PEG3-acid is a PEG linker containing a Boc-protected aminooxy group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions.

Uses

Boc-Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Boc-Aminooxy-PEG3-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Aminooxy-PEG3-acid Suppliers

China 30 United States 2 Global 32

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
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Jinan elephant international trading co., LTD

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Amatek Scientific Co. Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Hangzhou Taorui Biotechnology Co., Ltd

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Zhengzhou Akem Chemical Co., Ltd

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View Lastest Price from Boc-Aminooxy-PEG3-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: t-Boc-Aminooxy-PEG3-acid 1835759-82-4
Price: US $0.00/mg
Min. Order: 250mg
Purity: >98.00%
Supply Ability: 250mg
Release date: 2024-03-22

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Boc-Aminooxy-PEG3-acid

t-Boc-Aminooxy-PEG3-acid

N-Boc-Aminooxy-PEG3-acid

3,6,9,12-Tetraoxa-2-azapentadecanedioic acid, 1-(1,1-dimethylethyl) ester

1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10-tetraoxatridecan-13-oic acid

t-Boc-Aminooxy-PEG3-acid t-Boc-

BocHNO-PEG3-CH2CH2COOH

2,2-Dimethyl-4-oxo-3,6,9,12,15-pentaoxa-5-azaoctadecan-18-oic acid

1835759-82-4