t-Boc-Aminoxy-PEG3-Azide
- Product Name
- t-Boc-Aminoxy-PEG3-Azide
- CAS No.
- 1235514-15-4
- Chemical Name
- t-Boc-Aminoxy-PEG3-Azide
- Synonyms
- Boc-Aminoxy-PEG3-N3;Boc-Aminooxy-PEG3-Azide;t-Boc-Aminoxy-PEG3-Azide;t-Boc-Aminooxy-PEG3-azide;t-Boc-Aminooxy-PEG3-azide boc;tert-butyl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethoxycarbamate
- CBNumber
- CB13062660
- Molecular Formula
- C13H26N4O6
- Formula Weight
- 334.37
- MOL File
- 1235514-15-4.mol
N-Bromosuccinimide Price
- Product number
- B811715
- Product name
- t-Boc-aminooxy-peg3-azide
- Packaging
- 5mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- B811715
- Product name
- t-Boc-aminooxy-peg3-azide
- Packaging
- 50mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- BP-22761
- Product name
- t-Boc-Aminooxy-PEG3-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-22761
- Product name
- t-Boc-Aminooxy-PEG3-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BIPG1796
- Product name
- t-Boc-Aminoxy-PEG3-Azide
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
t-Boc-Aminoxy-PEG3-Azide Chemical Properties,Usage,Production
Description
t-Boc-Aminooxy-PEG3-azide is a click chemistry reagent containing a t-Boc-aminooxy group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The protected aminooxy can be deprotected under mild acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-Aminooxy-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413. DOI:10.1124/pr.118.015651
t-Boc-Aminoxy-PEG3-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from t-Boc-Aminoxy-PEG3-Azide manufacturers
- Product
- t-Boc-Aminooxy-PEG3-azide 1235514-15-4
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22