t-Boc-N-amido-PEG1-NHS ester
- Product Name
- t-Boc-N-amido-PEG1-NHS ester
- CAS No.
- 1260092-55-4
- Chemical Name
- t-Boc-N-amido-PEG1-NHS ester
- Synonyms
- t-Boc-N-amido-PEG1-NHS;Boc-N-PEG1-C2-NHS ester;BocNH-PEG1-CH2CH2COONHS;t-Boc-N-amido-PEG1-NHS ester;BocNH-PEG1-CH2CH2COONHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate;Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB54849668
- Molecular Formula
- C14H22N2O7
- Formula Weight
- 330.33
- MOL File
- 1260092-55-4.mol
t-Boc-N-amido-PEG1-NHS ester Property
- Density
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- Storage temp. -20°C
- pka
- 12.21±0.46(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- BP-23959
- Product name
- t-Boc-N-amido-PEG1-NHSester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23959
- Product name
- t-Boc-N-amido-PEG1-NHSester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- AS107902
- Product name
- BocNH-PEG1-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $580
- Updated
- 2021/12/16
- Product number
- BP-23959
- Product name
- t-Boc-N-amido-PEG1-NHSester
- Purity
- 98%
- Packaging
- 1g
- Price
- $870
- Updated
- 2021/12/16
- Product number
- A581867
- Product name
- 2,5-Dioxopyrrolidin-1-yl3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
- Purity
- 98%
- Packaging
- 5g
- Price
- $645
- Updated
- 2021/12/16
t-Boc-N-amido-PEG1-NHS ester Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-amido-PEG1-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-amido-PEG1-NHS ester Suppliers
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View Lastest Price from t-Boc-N-amido-PEG1-NHS ester manufacturers
- Product
- t-Boc-N-amido-PEG1-NHS 1260092-55-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-05
- Product
- BocNH-PEG1-CH2CH2COONHS ester 1260092-55-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2026-01-29
- Product
- t-Boc-N-amido-PEG1-NHS ester 1260092-55-4
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25