ChemicalBook > CAS DataBase List > t-Boc-N-amido-PEG1-NHS ester

t-Boc-N-amido-PEG1-NHS ester

Product Name
t-Boc-N-amido-PEG1-NHS ester
CAS No.
1260092-55-4
Chemical Name
t-Boc-N-amido-PEG1-NHS ester
Synonyms
Boc-N-PEG1-C2-NHS ester;BocNH-PEG1-CH2CH2COONHS;t-Boc-N-amido-PEG1-NHS ester;BocNH-PEG1-CH2CH2COONHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate;Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB54849668
Molecular Formula
C14H22N2O7
Formula Weight
330.33
MOL File
1260092-55-4.mol
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t-Boc-N-amido-PEG1-NHS ester Property

Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Storage temp. -20°C
pka
12.21±0.46(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
250mg
Price
$380
Updated
2021/12/16
BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
500mg
Price
$580
Updated
2021/12/16
Activate Scientific
Product number
AS107902
Product name
BocNH-PEG1-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$580
Updated
2021/12/16
BroadPharm
Product number
BP-23959
Product name
t-Boc-N-amido-PEG1-NHSester
Purity
98%
Packaging
1g
Price
$870
Updated
2021/12/16
Ambeed
Product number
A581867
Product name
2,5-Dioxopyrrolidin-1-yl3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
Purity
98%
Packaging
5g
Price
$645
Updated
2021/12/16
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t-Boc-N-amido-PEG1-NHS ester Chemical Properties,Usage,Production

Description

t-Boc-N-amido-PEG1-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Boc-N-PEG1-C2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-amido-PEG1-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG1-NHS ester Suppliers

Shanghai Raise Chemical Technology Co.,Ltd
Tel
15026594951
Fax
0556-5030632
Email
rs@raise-chem.com
Country
China
ProdList
4454
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
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58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
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China
ProdList
28785
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58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
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0371-63284658 18135795563
Fax
QQ:2885349392
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2885349392@qq.com
Country
China
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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Zhengzhou Akem Chemical Co., Ltd
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3001317055@qq.com
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China
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80514535 19917294565
Email
et@chemextension.com
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China
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
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24961
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Shanghai Haohong Scientific Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
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China
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39845
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Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564 13854185395;
Email
info@easycdmo.com
Country
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Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
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Shandong fen Boyu Biotechnology Co.,LTD
Tel
13356310019 13356310019;
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Honghanyanxin Pharm
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0551-62626652 19334025048
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sales-honghanyanxin@aliyun.com
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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anhua.mao@aladdin-e.com
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China
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Jilin Chinese Academy of Sciences-yanshen Technology
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18143011203
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ET-market@chemextension.com
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32048
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Shanghai Yanfen Biochemical Technology Co.,LTD
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Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.
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Henan Mengtai Pharmaceutical Technology Co., Ltd
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Email
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10000
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Aikon International Limited
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025-58859352 18651614124
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LAURENT.INC
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LAURENT
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+undefined18100176782
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China
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365
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Xian confluore Biological Technology Co., Ltd.
Tel
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Jilin Chinese Academy of Sciences-yanshen Technology
Tel
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info@chemextension.com
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42056
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Shanghai Shitang Industrial Co., Ltd.
Tel
17301778918
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View Lastest Price from t-Boc-N-amido-PEG1-NHS ester manufacturers

LAURENT
Product
BocNH-PEG1-CH2CH2COONHS ester 1260092-55-4
Price
US $507.00/g
Min. Order
1g
Purity
98%
Supply Ability
300kg
Release date
2025-11-22
Xian confluore Biological Technology Co., Ltd.
Product
t-Boc-N-amido-PEG1-NHS ester 1260092-55-4
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1260092-55-4, t-Boc-N-amido-PEG1-NHS esterRelated Search:


  • t-Boc-N-amido-PEG1-NHS ester
  • BocNH-PEG1-CH2CH2COONHS
  • Boc-N-PEG1-C2-NHS ester
  • 2,5-Dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
  • BocNH-PEG1-CH2CH2COONHS/Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • Propanoic acid, 3-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • BocNH-PEG1-CH2CH2COONHS ester
  • 1260092-55-4