t-Boc-N-Amido-PEG4-Azide
- Product Name
- t-Boc-N-Amido-PEG4-Azide
- CAS No.
- 940951-99-5
- Chemical Name
- t-Boc-N-Amido-PEG4-Azide
- Synonyms
- BocNH-P5-N3;N3-PEG4-NH-BOC;Boc-NH-PEG4-N3;Boc-NH-PEG4-azide;BocNH-PEG4-CH2CH2N3;Azido-PEG4-Boc Amine;Boc-N-Amido-PEG4-Azide;t-Boc-N-Amido-PEG4-Azide;tert-Butyl (14-azido-3,6,9,12-tetraoxatetradecyl)carbamate;BocNH-PEG4-CH2CH2N3/5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB23062667
- Molecular Formula
- C15H30N4O6
- Formula Weight
- 362.43
- MOL File
- 940951-99-5.mol
N-Bromosuccinimide Price
- Product number
- B601890
- Product name
- T-Boc-N-amido-PEG4-azide
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS103994
- Product name
- BocNH-PEG4-CH2CH2N3
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $248
- Updated
- 2021/12/16
- Product number
- BP-22155
- Product name
- t-Boc-N-Amido-PEG4-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- BP-22155
- Product name
- t-Boc-N-Amido-PEG4-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
- Product number
- AS103994
- Product name
- BocNH-PEG4-CH2CH2N3
- Purity
- 95+%
- Packaging
- 1g
- Price
- $489
- Updated
- 2021/12/16
t-Boc-N-Amido-PEG4-Azide Chemical Properties,Usage,Production
Description
t-Boc-N-Amido-PEG4-azide is a N-Boc protected PEG reagent. It can react with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG4-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-Amido-PEG4-Azide Suppliers
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View Lastest Price from t-Boc-N-Amido-PEG4-Azide manufacturers
- Product
- Azido-PEG4-NHBoc 940951-99-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23