t-Boc-N-Amido-PEG4-Azide
- Product Name
- t-Boc-N-Amido-PEG4-Azide
- CAS No.
- 940951-99-5
- Chemical Name
- t-Boc-N-Amido-PEG4-Azide
- Synonyms
- BocNH-P5-N3;N3-PEG4-NH-BOC;Boc-NH-PEG4-N3;Boc-NH-PEG4-azide;BocNH-PEG4-CH2CH2N3;Azido-PEG4-Boc Amine;Boc-N-Amido-PEG4-Azide;t-Boc-N-Amido-PEG4-Azide;tert-Butyl (14-azido-3,6,9,12-tetraoxatetradecyl)carbamate;BocNH-PEG4-CH2CH2N3/5,8,11,14-Tetraoxa-2-azahexadecanoic acid, 16-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB23062667
- Molecular Formula
- C15H30N4O6
- Formula Weight
- 362.43
- MOL File
- 940951-99-5.mol
t-Boc-N-Amido-PEG4-Azide Property
- storage temp.
- Store at Room Tem.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B601890
- Product name
- T-Boc-N-amido-PEG4-azide
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS103994
- Product name
- BocNH-PEG4-CH2CH2N3
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $248
- Updated
- 2021/12/16
- Product number
- BP-22155
- Product name
- t-Boc-N-Amido-PEG4-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- BP-22155
- Product name
- t-Boc-N-Amido-PEG4-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $400
- Updated
- 2021/12/16
- Product number
- AS103994
- Product name
- BocNH-PEG4-CH2CH2N3
- Purity
- 95+%
- Packaging
- 1g
- Price
- $489
- Updated
- 2021/12/16
t-Boc-N-Amido-PEG4-Azide Chemical Properties,Usage,Production
Description
t-Boc-N-Amido-PEG4-azide is a N-Boc protected PEG reagent. It can react with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-NH-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG4-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from t-Boc-N-Amido-PEG4-Azide manufacturers
- Product
- Azido-PEG4-NHBoc 940951-99-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23