t-Boc-Aminoxy-PEG4-alcohol
- Product Name
- t-Boc-Aminoxy-PEG4-alcohol
- CAS No.
- 918132-14-6
- Chemical Name
- t-Boc-Aminoxy-PEG4-alcohol
- Synonyms
- Boc-Aminooxy-PEG4;Reaxys ID: 11161875;Boc-Aminoxy-PEG4-OH;Boc-Aminooxy-PEG4-alcohol;t-Boc-Aminoxy-PEG4-alcohol;t-Boc-Aminooxy-PEG4-alcohol;t-Boc-Aminooxy-PEG4-alcohol boc;2-[2-[2-[2-[(Boc-amino)oxy]ethoxy]ethoxy]ethoxy]ethanol;tert-Butyl (2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethoxy)carbamate;3,6,9,12-Tetraoxa-2-azatetradecanoic acid, 14-hydroxy-, 1,1-dimethylethyl ester
- CBNumber
- CB43062661
- Molecular Formula
- C13H27NO7
- Formula Weight
- 309.36
- MOL File
- 918132-14-6.mol
t-Boc-Aminoxy-PEG4-alcohol Property
- Density
- 1.111±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 14.36±0.10(Predicted)
- form
- Viscous Liquid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-22228
- Product name
- t-Boc-Aminooxy-PEG4-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- BP-22228
- Product name
- t-Boc-Aminooxy-PEG4-alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $760
- Updated
- 2021/12/16
- Product number
- BIPG1795
- Product name
- t-Boc-Aminoxy-PEG4-alcohol
- Packaging
- 500mg
- Price
- $837
- Updated
- 2021/12/16
- Product number
- BP-22228
- Product name
- t-Boc-Aminooxy-PEG4-alcohol
- Purity
- 98%
- Packaging
- 5G
- Price
- $2650
- Updated
- 2021/12/16
t-Boc-Aminoxy-PEG4-alcohol Chemical Properties,Usage,Production
Description
t-Boc-Aminooxy-PEG4-alcohol is a PEGreagent with a Boc-protected aminooxy group and an alcohol group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected aminooxy can be deprotected under mild acidic conditions and then can react with an aldehyde to form a stable oxime linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Uses
Boc-Aminoxy-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-Aminoxy-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from t-Boc-Aminoxy-PEG4-alcohol manufacturers
- Product
- Boc-Aminooxy-PEG4 918132-14-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23