t-boc-N-amido-PEG5-azide
- Product Name
- t-boc-N-amido-PEG5-azide
- CAS No.
- 911209-07-9
- Chemical Name
- t-boc-N-amido-PEG5-azide
- Synonyms
- Azido-PEG5-NHBoc;Boc-NH-PEG5-azide;BocNH-PEG5-CH2CH2N3;Azido-PEG5-Boc Amine;t-boc-N-amido-PEG5-Azido;tert-Butyl (17-azido-3,6,9,12,15-pentaoxaheptadecyl)carbamate;BocNH-PEG5-CH2CH2N3/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 1,1-dimethylethyl ester
- CBNumber
- CB53364018
- Molecular Formula
- C17H34N4O7
- Formula Weight
- 406.47446
- MOL File
- 911209-07-9.mol
t-boc-N-amido-PEG5-azide Property
- storage temp.
- Store at Room Tem.
- solubility
- Soluble in Water, DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P999448
- Product name
- t-Boc-N-amido-PEG5-azide
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- AS104037
- Product name
- BocNH-PEG5-CH2CH2N3
- Purity
- 95+%
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
- Product number
- 8378DP
- Product name
- Boc-NH-PEG5-azide
- Packaging
- 5g
- Price
- $771
- Updated
- 2021/12/16
- Product number
- B-0916
- Product name
- BocNH-PEG5-CH2CH2N3
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $183.34
- Updated
- 2021/12/16
- Product number
- SC-28167
- Product name
- T-BOC-N-AMIDO-PEG5-AZIDO
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $360
- Updated
- 2021/12/16
t-boc-N-amido-PEG5-azide Chemical Properties,Usage,Production
Description
t-boc-N-amido-PEG5-azide is N-Boc protected crosslinker. The hydrophilic PEG spacer increases solubility in aqueous media. the compound can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Uses
Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-boc-N-amido-PEG5-azide Preparation Products And Raw materials
Raw materials
Preparation Products
t-boc-N-amido-PEG5-azide Suppliers
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View Lastest Price from t-boc-N-amido-PEG5-azide manufacturers
- Product
- Azido-PEG5-NHBoc 911209-07-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23