t-boc-N-amido-PEG5-azide

Product Name: t-boc-N-amido-PEG5-azide
CAS No.: 911209-07-9
Chemical Name: t-boc-N-amido-PEG5-azide
Synonyms: Azido-PEG5-NHBoc;Boc-NH-PEG5-azide;BocNH-PEG5-CH2CH2N3;Azido-PEG5-Boc Amine;t-boc-N-amido-PEG5-Azido;tert-Butyl (17-azido-3,6,9,12,15-pentaoxaheptadecyl)carbamate;BocNH-PEG5-CH2CH2N3/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 1,1-dimethylethyl ester
CBNumber: CB53364018
Molecular Formula: C17H34N4O7
Formula Weight: 406.47446
MOL File: 911209-07-9.mol

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t-boc-N-amido-PEG5-azide Property

storage temp.: Store at Room Tem.
solubility: Soluble in Water, DMSO, DCM, DMF

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P999448
Product name: t-Boc-N-amido-PEG5-azide
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Activate Scientific

Product number: AS104037
Product name: BocNH-PEG5-CH2CH2N3
Purity: 95+%
Packaging: 1g
Price: $532
Updated: 2021/12/16

AK Scientific

Product number: 8378DP
Product name: Boc-NH-PEG5-azide
Packaging: 5g
Price: $771
Updated: 2021/12/16

Acrotein

Product number: B-0916
Product name: BocNH-PEG5-CH2CH2N3
Purity: 97%
Packaging: 0.25g
Price: $183.34
Updated: 2021/12/16

SynChem

Product number: SC-28167
Product name: T-BOC-N-AMIDO-PEG5-AZIDO
Purity: 95+%
Packaging: 100mg
Price: $360
Updated: 2021/12/16

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t-boc-N-amido-PEG5-azide Chemical Properties,Usage,Production

Description

t-boc-N-amido-PEG5-azide is N-Boc protected crosslinker. The hydrophilic PEG spacer increases solubility in aqueous media. the compound can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-boc-N-amido-PEG5-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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t-boc-N-amido-PEG5-azide Suppliers

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View Lastest Price from t-boc-N-amido-PEG5-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG5-NHBoc 911209-07-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

911209-07-9, t-boc-N-amido-PEG5-azideRelated Search:

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t-boc-N-amido-PEG5-Azido

BocNH-PEG5-CH2CH2N3

tert-Butyl (17-azido-3,6,9,12,15-pentaoxaheptadecyl)carbamate

Azido-PEG5-NHBoc

Boc-NH-PEG5-azide

Azido-PEG5-Boc Amine

BocNH-PEG5-CH2CH2N3/5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 1,1-dimethylethyl ester

911209-07-9

C17H34N4O7