t-Boc-N-Amido-PEG6-Propargyl
- Product Name
- t-Boc-N-Amido-PEG6-Propargyl
- CAS No.
- 1262991-52-5
- Chemical Name
- t-Boc-N-Amido-PEG6-Propargyl
- Synonyms
- Propargyl-PEG6-NHBoc;Boc-NH-PEG6-propargyl;Propargyl-PEG7-Boc Amine;T-Boc-N-amino-PEG6-propargyl;t-Boc-N-Amido-PEG6-Propargyl;5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester;Propargyl-PEG6-NHBoc/5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester
- CBNumber
- CB93364021
- Molecular Formula
- C20H37NO8
- Formula Weight
- 419.51
- MOL File
- 1262991-52-5.mol
t-Boc-N-Amido-PEG6-Propargyl Property
- solubility
- Soluble in DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-23460
- Product name
- t-Boc-N-Amido-PEG6-propargyl
- Purity
- 98%
- Packaging
- 250mg
- Price
- $520
- Updated
- 2021/12/16
- Product number
- BP-23460
- Product name
- t-Boc-N-Amido-PEG6-propargyl
- Purity
- 98%
- Packaging
- 500mg
- Price
- $720
- Updated
- 2021/12/16
- Product number
- BP-23460
- Product name
- t-Boc-N-Amido-PEG6-propargyl
- Purity
- 98%
- Packaging
- 1g
- Price
- $1050
- Updated
- 2021/12/16
- Product number
- B-1346
- Product name
- Propargyl-PEG6-NHBoc
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $247.5
- Updated
- 2021/12/16
t-Boc-N-Amido-PEG6-Propargyl Chemical Properties,Usage,Production
Description
t-Boc-N-Amido-PEG6-propargyl can be used in copper catalyzed Click Chemistry reactions with azides. The Boc group can be removed under mild acidic conditions to yield the free amine.
Uses
Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
t-Boc-N-Amido-PEG6-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
t-Boc-N-Amido-PEG6-Propargyl Suppliers
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View Lastest Price from t-Boc-N-Amido-PEG6-Propargyl manufacturers
- Product
- Propargyl-PEG6-NHBoc 1262991-52-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26