ChemicalBook > CAS DataBase List > t-Boc-N-Amido-PEG6-Propargyl

t-Boc-N-Amido-PEG6-Propargyl

Product Name
t-Boc-N-Amido-PEG6-Propargyl
CAS No.
1262991-52-5
Chemical Name
t-Boc-N-Amido-PEG6-Propargyl
Synonyms
Propargyl-PEG6-NHBoc;Boc-NH-PEG6-propargyl;Propargyl-PEG7-Boc Amine;T-Boc-N-amino-PEG6-propargyl;t-Boc-N-Amido-PEG6-Propargyl;5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester;Propargyl-PEG6-NHBoc/5,8,11,14,17,20-Hexaoxa-2-azatricos-22-ynoic acid, 1,1-dimethylethyl ester
CBNumber
CB93364021
Molecular Formula
C20H37NO8
Formula Weight
419.51
MOL File
1262991-52-5.mol
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t-Boc-N-Amido-PEG6-Propargyl Property

solubility 
Soluble in DMSO, DCM, DMF
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23460
Product name
t-Boc-N-Amido-PEG6-propargyl
Purity
98%
Packaging
250mg
Price
$520
Updated
2021/12/16
BroadPharm
Product number
BP-23460
Product name
t-Boc-N-Amido-PEG6-propargyl
Purity
98%
Packaging
500mg
Price
$720
Updated
2021/12/16
BroadPharm
Product number
BP-23460
Product name
t-Boc-N-Amido-PEG6-propargyl
Purity
98%
Packaging
1g
Price
$1050
Updated
2021/12/16
Acrotein
Product number
B-1346
Product name
Propargyl-PEG6-NHBoc
Purity
97%
Packaging
0.25g
Price
$247.5
Updated
2021/12/16
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t-Boc-N-Amido-PEG6-Propargyl Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG6-propargyl can be used in copper catalyzed Click Chemistry reactions with azides. The Boc group can be removed under mild acidic conditions to yield the free amine.

Uses

Boc-NH-PEG6-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG6-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG6-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-Amido-PEG6-Propargyl Suppliers

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View Lastest Price from t-Boc-N-Amido-PEG6-Propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG6-NHBoc 1262991-52-5
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26