t-Boc-N-Amido-PEG3-propargyl

Product Name: t-Boc-N-Amido-PEG3-propargyl
CAS No.: 1333880-60-6
Chemical Name: t-Boc-N-Amido-PEG3-propargyl
Synonyms: Propargyl-PEG3-NHBoc;Boc-NH-PEG3-propargyl;Boc-N-Amido-PEG3-Alkyne;Propargyl-PEG4-Boc Amine;t-Boc-N-Amido-PEG3-propargyl;tert-butyl N-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethyl]carbamate;tert-Butyl (2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)carbamate;5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,?1-?dimethylethyl ester;Propargyl-PEG3-NHBoc/5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,1-dimethylethyl ester
CBNumber: CB33364014
Molecular Formula: C14H25NO5
Formula Weight: 287.35
MOL File: 1333880-60-6.mol

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t-Boc-N-Amido-PEG3-propargyl Property

Boiling point:: 386.4±32.0 °C(Predicted)
Density: 1.045±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
pka: 12.22±0.46(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23500
Product name: t-Boc-N-Amido-PEG3-propargyl
Purity: 98%
Packaging: 500mg
Price: $620
Updated: 2021/12/16

Aaron Chemicals

Product number: AR019F00
Product name: t-Boc-N-Amido-PEG3-propargyl
Purity: 95%
Packaging: 100mg
Price: $99
Updated: 2021/12/16

Acrotein

Product number: B-1344
Product name: Propargyl-PEG3-NHBoc
Purity: 97%
Packaging: 0.25g
Price: $183.3
Updated: 2021/12/16

Aaron Chemicals

Product number: AR019F00
Product name: t-Boc-N-Amido-PEG3-propargyl
Purity: 95%
Packaging: 250mg
Price: $191
Updated: 2021/12/16

Aaron Chemicals

Product number: AR019F00
Product name: t-Boc-N-Amido-PEG3-propargyl
Purity: 95%
Packaging: 1g
Price: $545
Updated: 2021/12/16

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t-Boc-N-Amido-PEG3-propargyl Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG3-propargyl enables formation of triazole linkage with azide-bearing compound via copper catalyzed Click Chemistry. Under mild acidic conditions, t-Boc group can be removed to yield the free amine.

Uses

Boc-NH-PEG3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG3-propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-Amido-PEG3-propargyl Suppliers

China 43 United States 3 Global 46

Xia Men Immortal Biomedical Technology Co., Ltd

Tel: 18558738213
Email: 1103898430@qq.com
Country: China
ProdList: 122
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 42446
Advantage: 60

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Jinan elephant international trading co., LTD

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Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 8927
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

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View Lastest Price from t-Boc-N-Amido-PEG3-propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG3-NHBoc 1333880-60-6
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-26

1333880-60-6, t-Boc-N-Amido-PEG3-propargylRelated Search:

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t-Boc-N-Amido-PEG3-propargyl

Propargyl-PEG3-NHBoc

Boc-N-Amido-PEG3-Alkyne

Boc-NH-PEG3-propargyl

5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,?1-?dimethylethyl ester

tert-Butyl (2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)carbamate

Propargyl-PEG4-Boc Amine

Propargyl-PEG3-NHBoc/5,8,11-Trioxa-2-azatetradec-13-ynoic acid, 1,1-dimethylethyl ester

tert-butyl N-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethyl]carbamate

1333880-60-6

1333800-60-6

SiChem