Thiol-dPEG4-t-boc-N-amido
- Product Name
- Thiol-dPEG4-t-boc-N-amido
- CAS No.
- 1895922-68-5
- Chemical Name
- Thiol-dPEG4-t-boc-N-amido
- Synonyms
- Thiol-PEG3-NHBoc;BocNH-PEG3-CH2CH2SH;Boc-N-amido-PEG3-thiol;t-Boc-N-amido-PEG3-thiol;Thiol-dPEG4-t-boc-N-amido;5,8,11-Trioxa-2-azatridecanoic acid, 13-mercapto-, 1,1-dimethylethyl ester;BocNH-PEG3-CH2CH2SH/5,8,11-Trioxa-2-azatridecanoic acid, 13-mercapto-, 1,1-dimethylethyl ester
- CBNumber
- CB33146564
- Molecular Formula
- C13H27NO5S
- Formula Weight
- 309.42
- MOL File
- 1895922-68-5.mol
Thiol-dPEG4-t-boc-N-amido Property
- Boiling point:
- 419.4±40.0 °C(Predicted)
- Density
- 1.072±0.06 g/cm3(Predicted)
- pka
- 9+-.0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS106460
- Product name
- BocNH-PEG3-CH2CH2SH
- Purity
- 97%
- Packaging
- 250mg
- Price
- $311
- Updated
- 2021/12/16
- Product number
- AS106460
- Product name
- BocNH-PEG3-CH2CH2SH
- Purity
- 97%
- Packaging
- 1g
- Price
- $679
- Updated
- 2021/12/16
- Product number
- B-1500
- Product name
- BocNH-PEG3-CH2CH2SH
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $223.67
- Updated
- 2021/12/16
- Product number
- B-1500
- Product name
- BocNH-PEG3-CH2CH2SH
- Purity
- 97%
- Packaging
- 1g
- Price
- $513.33
- Updated
- 2021/12/16
Thiol-dPEG4-t-boc-N-amido Chemical Properties,Usage,Production
Description
t-Boc-N-amido-PEG3-thiol is a PEG derivative containing a Boc-protected amino group and a thiol group. The Boc group can be deprotected under mild acidic conditions to form the free amine. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
Uses
Thiol-PEG3-NHBoc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014. DOI:10.1016/j.chembiol.2020.07.020
Thiol-dPEG4-t-boc-N-amido Preparation Products And Raw materials
Raw materials
Preparation Products
Thiol-dPEG4-t-boc-N-amido Suppliers
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View Lastest Price from Thiol-dPEG4-t-boc-N-amido manufacturers
- Product
- t-Boc-N-amido-PEG3-thiol 1895922-68-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27