alpha-lipoic acid-NHS

Product Name: alpha-lipoic acid-NHS
CAS No.: 40846-94-4
Chemical Name: alpha-lipoic acid-NHS
Synonyms: lipoic acid-NHS;α-Lipoic acid-NHS;DL-α-Lipoic Acid-NHS;alpha-lipoic acid-NHS;N-Hydroxysuccinimidyl Lipoate;Thioctic acid N-hydroxysuccinimide ester;1,2-Dithiolane-3-pentanoic acid succinimidyl ester, 95%;2,5-Dioxopyrrolidin-1-yl 5-(1,2-Dithiolan-3-yl)pentanoate;1,2-Dithiolane-3-pentanoic acid, 2,5-dioxo-1-pyrrolidinyl ester;5-(1,2-Dithiolan-3-yl)pentanic Acid 2,5-Dioxopyrrolidin-1-yl Ester
CBNumber: CB53162829
Molecular Formula: C12H17NO4S2
Formula Weight: 303.4
MOL File: 40846-94-4.mol

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alpha-lipoic acid-NHS Property

Melting point:: 95 °C
Boiling point:: 437.1±28.0 °C(Predicted)
Density: 1.36±0.1(20.0000℃)
solubility: Soluble in DMSO, DMF, DCM
form: powder to crystal
color: White to Yellow to Orange

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Safety

HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: L0345
Product name: DL-α-Lipoic Acid-NHS
Packaging: 50MG
Price: $136
Updated: 2025/07/31

TCI Chemical

Product number: L0345
Product name: DL-α-Lipoic Acid-NHS
Packaging: 250MG
Price: $471
Updated: 2025/07/31

Matrix Scientific

Product number: 171373
Product name: Thioctic acid N-hydroxysuccinimide ester
Purity: 95%
Packaging: 1g
Price: $660
Updated: 2021/12/16

BroadPharm

Product number: BP-22515
Product name: alpha-lipoicacid-NHS
Purity: 95%
Packaging: 5G
Price: $1200
Updated: 2021/12/16

Matrix Scientific

Product number: 171373
Product name: Thioctic acid N-hydroxysuccinimide ester
Purity: 95%
Packaging: 5g
Price: $1238
Updated: 2021/12/16

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alpha-lipoic acid-NHS Chemical Properties,Usage,Production

Description

alpha-lipoic acid-NHS contains a lipoic acid group and a terminal NHS group. The NHS group can participate in reactions with primary amine groups to form amide bonds.

Uses

α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

alpha-lipoic acid-NHS Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha-lipoic acid-NHS Suppliers

Americas 1 China 39 Europe 1 India 3 Japan 1 United States 5 Global 50

Shanghai Huici Pharmaceutical Technology Co., LTD

Tel: 133-31922809 19372841038
Email: lixing@pharmahuici.com
Country: China
ProdList: 732
Advantage: 58

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
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Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 14948
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

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View Lastest Price from alpha-lipoic acid-NHS manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: lipoic acid-NHS 40846-94-4
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-27

40846-94-4, alpha-lipoic acid-NHSRelated Search:

α-Lipoic Acid Lipoic acid Lipoamido-PEG3-Azide Lipoamido-PEG2-alcohol Lipoamido-PEG4-acid Thiol-PEG3-acid Lipoamide-PEG3-Mal Thiol-dPEG4-t-boc-N-amido Lipoamido-PEG3-alcohol

lipoic acid-NHS

alpha-lipoic acid-NHS

Thioctic acid N-hydroxysuccinimide ester

1,2-Dithiolane-3-pentanoic acid succinimidyl ester, 95%

N-Hydroxysuccinimidyl Lipoate

2,5-Dioxopyrrolidin-1-yl 5-(1,2-Dithiolan-3-yl)pentanoate

5-(1,2-Dithiolan-3-yl)pentanic Acid 2,5-Dioxopyrrolidin-1-yl Ester

DL-α-Lipoic Acid-NHS

α-Lipoic acid-NHS

Thioctic acid (2,5-dioxopyrrolidin-1-yl 5-(1,2-dithiolan-3-yl)pentanoate)

1,2-Dithiolane-3-pentanoic acid, 2,5-dioxo-1-pyrrolidinyl ester

40846-94-4