Thiol-PEG3-acid

Product Name: Thiol-PEG3-acid
CAS No.: 1347750-82-6
Chemical Name: Thiol-PEG3-acid
Synonyms: SH-PEG3-COOH;HS-PEG3-COOH;Thiol-PEG3-acid;Thiol-PEG3-propionic acid;3-(2-(2-(2-Mercaptoethoxy)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]-
CBNumber: CB43062676
Molecular Formula: C9H18O5S
Formula Weight: 238.3
MOL File: 1347750-82-6.mol

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Thiol-PEG3-acid Property

Boiling point:: 377.5±37.0 °C(Predicted)
Density: 1.163±0.06 g/cm3(Predicted)
pka: 4.28±0.10(Predicted)
form: Liquid

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Safety

HS Code: 2930909899

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC

Product number: T351218
Product name: Thiol-PEG3-acid
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-21804
Product name: Thiol-PEG3-acid
Purity: 95%
Packaging: 1g
Price: $450
Updated: 2021/12/16

ChemPep

Product number: 282701
Product name: HS-PEG3-CH2CH2COOH
Packaging: 1g
Price: $555
Updated: 2021/12/16

ChemPep

Product number: 282701
Product name: HS-PEG3-CH2CH2COOH
Packaging: 5g
Price: $1388
Updated: 2021/12/16

purepeg

Product number: 438703
Product name: HS-PEG3-CH2CH2COOH
Purity: min.95%
Packaging: 250mg
Price: $165
Updated: 2021/12/16

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Thiol-PEG3-acid Chemical Properties,Usage,Production

Description

Thiol-PEG3-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Thiol-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Thiol-PEG3-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiol-PEG3-acid Suppliers

China 44 United Kingdom 1 United States 3 Global 48

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
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T&W GROUP

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Hunan HuaTeng Pharmaceutical Co., Ltd.,

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Tongling HengYou Biotechnology Co., Ltd.

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Borenpharm Co., Ltd

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Country: China
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Zhengzhou Acme Chemical Co., Ltd.

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Amatek Scientific Co. Ltd.

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Hangzhou HanLai Biochemical Technology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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Henan Alfachem Co.,Ltd.

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View Lastest Price from Thiol-PEG3-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Thiol-PEG3-acid 1347750-82-6
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-27

1347750-82-6, Thiol-PEG3-acidRelated Search:

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Thiol-PEG3-acid

Thiol-PEG3-propionic acid

SH-PEG3-COOH

HS-PEG3-COOH

Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]-

3-(2-(2-(2-Mercaptoethoxy)ethoxy)ethoxy)propanoic acid

1347750-82-6

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