ChemicalBook > CAS DataBase List > Thiol-PEG3-acid

Thiol-PEG3-acid

Product Name
Thiol-PEG3-acid
CAS No.
1347750-82-6
Chemical Name
Thiol-PEG3-acid
Synonyms
SH-PEG3-COOH;HS-PEG3-COOH;Thiol-PEG3-acid;Thiol-PEG3-propionic acid;3-(2-(2-(2-Mercaptoethoxy)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]-
CBNumber
CB43062676
Molecular Formula
C9H18O5S
Formula Weight
238.3
MOL File
1347750-82-6.mol
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Thiol-PEG3-acid Property

Boiling point:
377.5±37.0 °C(Predicted)
Density 
1.163±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
4.28±0.10(Predicted)
form 
Liquid
Appearance
Colorless to light yellow Liquid
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Safety

HS Code 
2930909899
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
T351218
Product name
Thiol-PEG3-acid
Packaging
5mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-21804
Product name
Thiol-PEG3-acid
Purity
95%
Packaging
1g
Price
$450
Updated
2021/12/16
ChemPep
Product number
282701
Product name
HS-PEG3-CH2CH2COOH
Packaging
1g
Price
$555
Updated
2021/12/16
ChemPep
Product number
282701
Product name
HS-PEG3-CH2CH2COOH
Packaging
5g
Price
$1388
Updated
2021/12/16
purepeg
Product number
438703
Product name
HS-PEG3-CH2CH2COOH
Purity
min.95%
Packaging
250mg
Price
$165
Updated
2021/12/16
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Thiol-PEG3-acid Chemical Properties,Usage,Production

Description

Thiol-PEG3-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Thiol-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Thiol-PEG3-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiol-PEG3-acid Suppliers

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View Lastest Price from Thiol-PEG3-acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Thiol-PEG3-acid 1347750-82-6
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-27

1347750-82-6, Thiol-PEG3-acidRelated Search:

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  • Thiol-PEG3-acid
  • Thiol-PEG3-propionic acid
  • SH-PEG3-COOH
  • HS-PEG3-COOH
  • Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]-
  • 3-(2-(2-(2-Mercaptoethoxy)ethoxy)ethoxy)propanoic acid
  • 1347750-82-6
  • peg