Thiol-PEG2-acid

Product Name: Thiol-PEG2-acid
CAS No.: 1379649-73-6
Chemical Name: Thiol-PEG2-acid
Synonyms: SH-PEG2-PA;HS-PEG2-COOH;SH-PEG2-COOH;Thiol-PEG2-acid;SH-PEG2-CH2CH2COOH;HS-PEG2-CH2CH2COOH;mercaptoyl-dipolyethyldiol-carboxylic acid;3-[2-(2-Mercaptoethoxy)ethoxy]propanoic acid;Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-
CBNumber: CB13062675
Molecular Formula: C7H14O4S
Formula Weight: 194.25
MOL File: 1379649-73-6.mol

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Thiol-PEG2-acid Property

Boiling point:: 329.0±32.0 °C(Predicted)
Density: 1.173±0.06 g/cm3(Predicted)
storage temp.: Refrigerator, under inert atmosphere
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Oil
pka: 4.27±0.10(Predicted)
color: Colourless
Stability:: Air Sensitive

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Safety

HS Code: 2930909899

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T351220
Product name: Thiol-PEG2-acid
Packaging: 10mg
Price: $100
Updated: 2021/12/16

BroadPharm

Product number: BP-21807
Product name: Thiol-PEG2-acid
Purity: 95%
Packaging: 1g
Price: $320
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1836
Product name: Thiol-PEG2-acid
Packaging: 250mg
Price: $363
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1836
Product name: Thiol-PEG2-acid
Packaging: 500mg
Price: $457
Updated: 2021/12/16

Absolute Chiral

Product number: P1003-00-N
Product name: 3-(2-(2-mercaptoethoxy)ethoxy)propanoicacid
Purity: techgrade
Packaging: 100mg
Price: $188
Updated: 2021/12/16

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Thiol-PEG2-acid Chemical Properties,Usage,Production

Description

Thiol-PEG2-acid is a PEG linker containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Thiol-PEG2-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiol-PEG2-acid Suppliers

China 45 United Kingdom 1 United States 1 Global 47

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5873
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 17714375163
Email: yftan@aikonchem.com
Country: China
ProdList: 16676
Advantage: 50

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10028
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28772
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Shanghai UCHEM Inc.

Tel: +862156762820 +86-13564624040
Email: sales@myuchem.com
Country: China
ProdList: 8793
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

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View Lastest Price from Thiol-PEG2-acid manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: SH-PEG2-PA 1379649-73-6
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-06

Xian confluore Biological Technology Co., Ltd.

Product: Thiol-PEG2-acid 1379649-73-6
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-27

1379649-73-6, Thiol-PEG2-acidRelated Search:

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Thiol-PEG2-acid

HS-PEG2-CH2CH2COOH

SH-PEG2-COOH

HS-PEG2-COOH

Propanoic acid, 3-[2-(2-mercaptoethoxy)ethoxy]-

3-[2-(2-Mercaptoethoxy)ethoxy]propanoic acid

SH-PEG2-CH2CH2COOH

SH-PEG2-PA

mercaptoyl-dipolyethyldiol-carboxylic acid

1379649-73-6

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