Thiol-PEG3-t-butyl ester
- Product Name
- Thiol-PEG3-t-butyl ester
- CAS No.
- 1446282-39-8
- Chemical Name
- Thiol-PEG3-t-butyl ester
- Synonyms
- HS-PEG3-COOtBu;Thiol-PEG3-Boc;SH-PEG3-CH2CH2COOtBu;Thiol-PEG3-t-butyl ester;tert-Butyl 3-(2-(2-(2-mercaptoethoxy)ethoxy)ethoxy)propanoate;Propanoic acid, 3-[2-[2-(2-mercaptoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB73062677
- Molecular Formula
- C13H26O5S
- Formula Weight
- 294.41
- MOL File
- 1446282-39-8.mol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T351215
- Product name
- Thiol-PEG3-t-butylester
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-21803
- Product name
- Thiol-PEG3-t-butylester
- Purity
- 95%
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- BIPG1843
- Product name
- Thiol-PEG3-t-butyl ester
- Packaging
- 100mg
- Price
- $428
- Updated
- 2021/12/16
- Product number
- BP-21803
- Product name
- Thiol-PEG3-t-butylester
- Purity
- 95%
- Packaging
- 500mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- BP-21803
- Product name
- Thiol-PEG3-t-butylester
- Purity
- 95%
- Packaging
- 1g
- Price
- $980
- Updated
- 2021/12/16
Thiol-PEG3-t-butyl ester Chemical Properties,Usage,Production
Description
Thiol-PEG3-t-butyl ester is a PEG linker containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Thiol-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Thiol-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Thiol-PEG3-t-butyl ester manufacturers
- Product
- Thiol-PEG3-t-butyl ester 1446282-39-8
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-27