Lipoamido-PEG4-acid

Product Name: Lipoamido-PEG4-acid
CAS No.: 1314378-10-3
Chemical Name: Lipoamido-PEG4-acid
Synonyms: LA-PEG4-COOH;Lipoamido-PEG-acid;Lipoamido-PEG4-acid;LIPOAMIDO-PEG4-COOH;Lipoamido-PEG4-CH2CH2COOH;4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(1,2-dithiolan-3-yl)-17-oxo-;Lipoamido-PEG4-CH2CH2COOH/4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(1,2-dithiolan-3-yl)-17-oxo
CBNumber: CB63062519
Molecular Formula: C19H35NO7S2
Formula Weight: 453.61
MOL File: 1314378-10-3.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22164
Product name: Lipoamido-PEG4-acid
Purity: 95%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-22164
Product name: Lipoamido-PEG4-acid
Purity: 95%
Packaging: 250mg
Price: $530
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1465
Product name: Lipoamido-PEG4-acid
Packaging: 100mg
Price: $623
Updated: 2021/12/16

BroadPharm

Product number: BP-22164
Product name: Lipoamido-PEG4-acid
Purity: 95%
Packaging: 500mg
Price: $780
Updated: 2021/12/16

Acrotein

Product number: B-1556
Product name: Lipoamido-PEG4-CH2CH2COOH
Purity: 97%
Packaging: 0.5g
Price: $660
Updated: 2021/12/16

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Lipoamido-PEG4-acid Chemical Properties,Usage,Production

Description

Lipoamido-PEG4-acid contains a lipoic acid group and a terminal carboxylic acid. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of the compound.

Uses

Lipoamido-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Lipoamido-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Lipoamido-PEG4-acid Suppliers

China 20 United Kingdom 1 United States 2 Global 23

Hunan HuaTeng Pharmaceutical Co., Ltd.,

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TargetMol Chemicals Inc.

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Nextpeptide Inc

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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1314378-10-3, Lipoamido-PEG4-acidRelated Search:

Lipoamido-PEG3-Azide Lipoamido-PEG2-alcohol alpha-lipoic acid-NHS Thiol-PEG3-acid Thiol-dPEG4-t-boc-N-amido Lipoamido-PEG3-alcohol SPDP-PEG4-NHS ester MPEG8-NH-Mal Mal-PEG6-COOH Mal-PEG4-NHS ester PEG9-t-butly ester Azido-PEG2-CH2CO2-NHS Amino-PEG8-azide Azido-PEG2-acid Lipoamide-PEG3-Mal alpha, oMega-DisucciniMidyl triethylene glycol alpha, oMega-DisucciniMidyl diethylene glycol alpha, oMega-DisucciniMidyl hexaethylene glycol

Lipoamido-PEG4-acid

LA-PEG4-COOH

LIPOAMIDO-PEG4-COOH

Lipoamido-PEG4-CH2CH2COOH

4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(1,2-dithiolan-3-yl)-17-oxo-

Lipoamido-PEG-acid

Lipoamido-PEG4-CH2CH2COOH/4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-(1,2-dithiolan-3-yl)-17-oxo

1314378-10-3

C19H35NO7S2

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