alpha, oMega-DisucciniMidyl hexaethylene glycol
- Product Name
- alpha, oMega-DisucciniMidyl hexaethylene glycol
- CAS No.
- 1334170-02-3
- Chemical Name
- alpha, oMega-DisucciniMidyl hexaethylene glycol
- Synonyms
- NHS-PEG6-NHS;Di-NHS Ester-PEG7;Bis-PEG7-NHS ester;Bis-dPEG7-NHS ester;Bis-PEG7-NHS ester bis-;Bis-dPEG??-NHS ester (QBD-10988);NHSOOCCH2CH2O-PEG6-CH2CH2COONHS ester;α,ω-disuccinimidyl hexaethylene glycol;alpha, oMega-DisucciniMidyl hexaethylene glycol;4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester
- CBNumber
- CB02546993
- Molecular Formula
- C26H40N2O15
- Formula Weight
- 620.6
- MOL File
- 1334170-02-3.mol
alpha, oMega-DisucciniMidyl hexaethylene glycol Property
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Viscous Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- bp-20430
- Product name
- Bis-PEG7-NHS ester
- Purity
- 98%
- Packaging
- 100MG
- Price
- $260
- Updated
- 2026/05/24
- Product number
- bp-20430
- Product name
- Bis-PEG7-NHS ester
- Purity
- 98%
- Packaging
- 500MG
- Price
- $460
- Updated
- 2026/05/24
- Product number
- bp-20430
- Product name
- Bis-PEG7-NHS ester
- Purity
- 98%
- Packaging
- 1G
- Price
- $650
- Updated
- 2026/05/24
- Product number
- PEG3970
- Product name
- Bis-succinimidyl-4,7,10,13,16,19,22-heptaoxa pentacosane-1,25-dioate
- Packaging
- 100mg
- Price
- $564
- Updated
- 2026/05/19
- Product number
- PEG3970
- Product name
- Bis-succinimidyl-4,7,10,13,16,19,22-heptaoxa pentacosane-1,25-dioate
- Packaging
- 1g
- Price
- $960
- Updated
- 2026/05/19
alpha, oMega-DisucciniMidyl hexaethylene glycol Chemical Properties,Usage,Production
Description
Bis-PEG7-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Biological Activity
Bis-PEG7-NHS ester is a PROTAC bridge, belonging to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
target
| Cleavable
| PEGs
| Alkyl/ether
|
IC 50
Cleavable Linker; PEGs; Alkyl/ether
References
[1] Mahendra Persaud Deonarai, et al. Biological materials and uses thereof. WO2016046574A1
alpha, oMega-DisucciniMidyl hexaethylene glycol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from alpha, oMega-DisucciniMidyl hexaethylene glycol manufacturers
- Product
- Bis-PEG7-NHS ester 1334170-02-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25