alpha, oMega-DisucciniMidyl hexaethylene glycol

Product Name: alpha, oMega-DisucciniMidyl hexaethylene glycol
CAS No.: 1334170-02-3
Chemical Name: alpha, oMega-DisucciniMidyl hexaethylene glycol
Synonyms: NHS-PEG6-NHS;Di-NHS Ester-PEG7;Bis-PEG7-NHS ester;Bis-dPEG7-NHS ester;Bis-PEG7-NHS ester bis-;Bis-dPEG??-NHS ester (QBD-10988);NHSOOCCH2CH2O-PEG6-CH2CH2COONHS ester;α,ω-disuccinimidyl hexaethylene glycol;alpha, oMega-DisucciniMidyl hexaethylene glycol;4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester
CBNumber: CB02546993
Molecular Formula: C26H40N2O15
Formula Weight: 620.6
MOL File: 1334170-02-3.mol

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alpha, oMega-DisucciniMidyl hexaethylene glycol Property

storage temp.: Storage temp. -20°C
solubility: Soluble in DMSO, DCM, DMF
form: Viscous Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: B592853
Product name: Bis-PEG7-NHSEster
Packaging: 50mg
Price: $130
Updated: 2021/12/16

BroadPharm

Product number: BP-20430
Product name: Bis-PEG7-NHSester
Purity: 98%
Packaging: 100mg
Price: $260
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: LIN0000146
Product name: BIS-PEG7-NHS ESTER
Purity: 95.00%
Packaging: 5MG
Price: $445
Updated: 2021/12/16

BroadPharm

Product number: BP-20430
Product name: Bis-PEG7-NHSester
Purity: 98%
Packaging: 500mg
Price: $460
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG3970
Product name: NHS-dPEG™(7)-NHS
Packaging: 100mg
Price: $472.5
Updated: 2021/12/16

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alpha, oMega-DisucciniMidyl hexaethylene glycol Chemical Properties,Usage,Production

Description

Bis-PEG7-NHS ester is a PEG linker containing two NHS ester groups. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Bis-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Bis-PEG7-NHS ester is a PROTAC bridge, belonging to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

target

Cleavable

PEGs

Alkyl/ether

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Mahendra Persaud Deonarai, et al. Biological materials and uses thereof. WO2016046574A1

alpha, oMega-DisucciniMidyl hexaethylene glycol Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha, oMega-DisucciniMidyl hexaethylene glycol Suppliers

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View Lastest Price from alpha, oMega-DisucciniMidyl hexaethylene glycol manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Bis-PEG7-NHS ester 1334170-02-3
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

1334170-02-3, alpha, oMega-DisucciniMidyl hexaethylene glycolRelated Search:

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alpha, oMega-DisucciniMidyl hexaethylene glycol

NHS-PEG6-NHS

Bis-PEG7-NHS ester

α,ω-disuccinimidyl hexaethylene glycol

4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid, 1,25-bis(2,5-dioxo-1-pyrrolidinyl) ester

Bis-dPEG7-NHS ester

Di-NHS Ester-PEG7

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxo-propoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

Bis-PEG7-NHS ester bis-

Bis-dPEG??-NHS ester (QBD-10988)

NHSOOCCH2CH2O-PEG6-CH2CH2COONHS ester

1334170-02-3

C26H40N2O15

Homobifunctional PEG