Lipoamide-PEG3-Mal
- Product Name
- Lipoamide-PEG3-Mal
- CAS No.
- 1314378-19-2
- Chemical Name
- Lipoamide-PEG3-Mal
- Synonyms
- LA-PEG3-NH-Mal;Lipoamide-PEG3-Mal;LIPOAMIDE-PEG3-NH-MAL;1H-Pyrrole-1-propanamide, N-[19-(1,2-dithiolan-3-yl)-15-oxo-4,7,10-trioxa-14-azanonadec-1-yl]-2,5-dihydro-2,5-dioxo-
- CBNumber
- CB43062515
- Molecular Formula
- C25H41N3O7S2
- Formula Weight
- 559.74
- MOL File
- 1314378-19-2.mol
Lipoamide-PEG3-Mal Property
- form
- Solid
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- BP-22168
- Product name
- Lipoamide-PEG3-Mal
- Purity
- 95%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-22168
- Product name
- Lipoamide-PEG3-Mal
- Purity
- 95%
- Packaging
- 250mg
- Price
- $640
- Updated
- 2021/12/16
- Product number
- BIPG1463
- Product name
- Lipoamide-PEG3-Mal
- Packaging
- 100mg
- Price
- $740
- Updated
- 2021/12/16
- Product number
- BP-22168
- Product name
- Lipoamide-PEG3-Mal
- Purity
- 95%
- Packaging
- 500mg
- Price
- $890
- Updated
- 2021/12/16
Lipoamide-PEG3-Mal Chemical Properties,Usage,Production
Description
Lipoamide-PEG3-Mal contains a lipoic acid group and a terminal maleimide group. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG linker increases the water solubility of the compound.
Uses
Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Lipoamide-PEG3-Mal Preparation Products And Raw materials
Raw materials
Preparation Products
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