t-Boc-N-Amido-PEG5-propargyl

Product Name: t-Boc-N-Amido-PEG5-propargyl
CAS No.: 2062663-67-4
Chemical Name: t-Boc-N-Amido-PEG5-propargyl
Synonyms: BocNH-P5-Propargyl;Propargyl-PEG5-NHBoc;Boc-NH-PEG5-propargyl;Propargyl-PEG6-Boc Amine;t-Boc-N-Amido-PEG5-propargyl;(3,6,9,12,15-pentaoxaoctadecyl-17-yne-1-yl) tert Butyl carbamate;5,8,11,14,17-Pentaoxa-2-azaeicos-19-ynoic acid, 1,1-dimethylethyl ester;Propargyl-PEG5-NHBoc/5,8,11,14,17-Pentaoxa-2-azaeicos-19-ynoic acid, 1,1-dimethylethyl ester
CBNumber: CB63364020
Molecular Formula: C18H33NO7
Formula Weight: 375.46
MOL File: 2062663-67-4.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23459
Product name: t-Boc-N-Amido-PEG5-propargyl
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

BroadPharm

Product number: BP-23459
Product name: t-Boc-N-Amido-PEG5-propargyl
Purity: 98%
Packaging: 250mg
Price: $460
Updated: 2021/12/16

BroadPharm

Product number: BP-23459
Product name: t-Boc-N-Amido-PEG5-propargyl
Purity: 98%
Packaging: 1g
Price: $980
Updated: 2021/12/16

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t-Boc-N-Amido-PEG5-propargyl Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG5-propargyl comprises a propargyl group and Boc-protected amine. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Uses

Boc-NH-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-NH-PEG5-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-Amido-PEG5-propargyl Preparation Products And Raw materials

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t-Boc-N-Amido-PEG5-propargyl Suppliers

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Borenpharm Co., Ltd

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View Lastest Price from t-Boc-N-Amido-PEG5-propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG5-NHBoc 2062663-67-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-26

2062663-67-4, t-Boc-N-Amido-PEG5-propargylRelated Search:

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t-Boc-N-Amido-PEG5-propargyl

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(3,6,9,12,15-pentaoxaoctadecyl-17-yne-1-yl) tert Butyl carbamate

2062663-67-4