Aminoxy-PEG4-acid

Product Name: Aminoxy-PEG4-acid
CAS No.: 1807537-38-7
Chemical Name: Aminoxy-PEG4-acid
Synonyms: Aminoxy-PEG4-acid;Aminoxy-PEG4-COOH;Aminooxy-PEG4-acid;Aminooxy-PEG4-COOH;Aminooxy-PEG4-acid HCl salt;Hydroxylamine-tetraethylene glycol-carboxylic acid;Propanoic acid, 3-[2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]ethoxy]-
CBNumber: CB53062330
Molecular Formula: C11H23NO7
Formula Weight: 281.3
MOL File: 1807537-38-7.mol

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Aminoxy-PEG4-acid Property

Boiling point:: 448.6±45.0 °C(Predicted)
Density: 1.170±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DMF
pka: 4.28±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22136
Product name: Aminooxy-PEG4-acid
Purity: 98%
Packaging: 100mg
Price: $290
Updated: 2021/12/16

BroadPharm

Product number: BP-22136
Product name: Aminooxy-PEG4-acid
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1083
Product name: Aminoxy-PEG4-acid
Packaging: 100mg
Price: $681
Updated: 2021/12/16

BroadPharm

Product number: BP-22136
Product name: Aminooxy-PEG4-acid
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

BroadPharm

Product number: BP-22136
Product name: Aminooxy-PEG4-acid
Purity: 98%
Packaging: 1g
Price: $980
Updated: 2021/12/16

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Aminoxy-PEG4-acid Chemical Properties,Usage,Production

Description

Aminooxy-PEG4-acid is a PEG linker containing an aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. Aminooxy-PEG4-acid is not stable as a neat compound; it is sold as 1.0M aqueous solution.

Uses

Aminooxy-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Aminoxy-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Aminoxy-PEG4-acid Suppliers

China 34 United Kingdom 1 United States 2 Global 37

Hunan HuaTeng Pharmaceutical Co., Ltd.,

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View Lastest Price from Aminoxy-PEG4-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Aminooxy-PEG4-acid 1807537-38-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >98.00%
Supply Ability: 100mg
Release date: 2024-03-22

1807537-38-7, Aminoxy-PEG4-acidRelated Search:

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Aminoxy-PEG4-acid

Aminooxy-PEG4-acid

Aminoxy-PEG4-COOH

Aminooxy-PEG4-acid HCl salt

Aminooxy-PEG4-COOH

Propanoic acid, 3-[2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]ethoxy]-

Hydroxylamine-tetraethylene glycol-carboxylic acid

1807537-38-7

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