Aminoxy-PEG3-acid
- Product Name
- Aminoxy-PEG3-acid
- CAS No.
- 1807540-79-9
- Chemical Name
- Aminoxy-PEG3-acid
- Synonyms
- Aminoxy-PEG3-acid;Aminooxy-PEG3-acid;Aminooxy-PEG3-acid HCl salt;Propanoic acid, 3-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-
- CBNumber
- CB13062327
- Molecular Formula
- C9H19NO6
- Formula Weight
- 237.25
- MOL File
- 1807540-79-9.mol
Aminoxy-PEG3-acid Property
- Boiling point:
- 415.9±40.0 °C(Predicted)
- Density
- 1.181±0.06 g/cm3(Predicted)
- pka
- 4.28±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-21809
- Product name
- Aminooxy-PEG3-acidHClsalt
- Purity
- 98%
- Packaging
- 100mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- BIPG1082
- Product name
- Aminoxy-PEG3-acid
- Packaging
- 100mg
- Price
- $662
- Updated
- 2021/12/16
- Product number
- BP-21809
- Product name
- Aminooxy-PEG3-acidHClsalt
- Purity
- 98%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
Aminoxy-PEG3-acid Chemical Properties,Usage,Production
Description
Aminooxy-PEG3-acid HCl salt is a PEG linker containing an aminooxy group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Aminoxy-PEG3-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Aminoxy-PEG3-acid Suppliers
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View Lastest Price from Aminoxy-PEG3-acid manufacturers
- Product
- Aminooxy-PEG3-acid HCl salt 1807540-79-9
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-22