Aminooxy-PEG4-alcohol
- Product Name
- Aminooxy-PEG4-alcohol
- CAS No.
- 106492-60-8
- Chemical Name
- Aminooxy-PEG4-alcohol
- Synonyms
- HO-PEG4-ONH2;Aminooxy-PEG4-alcohol;Hydroxylamine-tetraethylene glycol;2-(2-(2-(2-(aminooxy)ethoxy)ethoxy)ethoxy)ethanol;Ethanol, 2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-;Aminooxy PEG4 alcohol,AminooxyPEG4alcohol,Aminooxy-PEG-4-alcohol
- CBNumber
- CB53373559
- Molecular Formula
- C8H19NO5
- Formula Weight
- 209.24
- MOL File
- 106492-60-8.mol
N-Bromosuccinimide Price
- Product number
- BP-23671
- Product name
- Aminooxy-PEG4-alcohol
- Purity
- 98%
- Packaging
- 250mg
- Price
- $580
- Updated
- 2021/12/16
- Product number
- BP-23671
- Product name
- Aminooxy-PEG4-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $820
- Updated
- 2021/12/16
Aminooxy-PEG4-alcohol Chemical Properties,Usage,Production
Description
Aminooxy-PEG4-alcohol is an aqueous soluble PEG reagent. The aminooxy group can react with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
IC 50
PEGs; Non-cleavable Linker
References
[1] Heather D. Maynard, et al. Method of creating hydrogels through oxime bond formation. US20150202305A1.
[2] Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3. DOI:10.1039/c0cc03856c
Aminooxy-PEG4-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Aminooxy-PEG4-alcohol manufacturers
- Product
- Aminooxy-PEG4-alcohol 106492-60-8
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22