Aminooxy-PEG3-t-butyl ester
- Product Name
- Aminooxy-PEG3-t-butyl ester
- CAS No.
- 1835759-72-2
- Chemical Name
- Aminooxy-PEG3-t-butyl ester
- Synonyms
- Aminooxy-PEG3-C2-Boc;Aminooxy-PEG3-t-butyl ester;Propanoic acid, 3-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB13162836
- Molecular Formula
- C13H27NO6
- Formula Weight
- 293.36
- MOL File
- 1835759-72-2.mol
Aminooxy-PEG3-t-butyl ester Property
- Boiling point:
- 392.4±32.0 °C(Predicted)
- Density
- 1.063±0.06 g/cm3(Predicted)
- pka
- 4.21±0.70(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-22961
- Product name
- Aminooxy-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $675
- Updated
- 2021/12/16
Aminooxy-PEG3-t-butyl ester Chemical Properties,Usage,Production
Description
Aminooxy-PEG3-t-butyl ester is an aminooxy-containing PEG molecule. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl ester can be converted tofree acid under acidic condition. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Aminooxy-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Aminooxy-PEG3-t-butyl ester manufacturers
- Product
- Aminooxy-PEG3-t-butyl ester 1835759-72-2
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-22