1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE
- Product Name
- 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE
- CAS No.
- 1076199-21-7
- Chemical Name
- 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE
- Synonyms
- BocNH-PEG3-Br;Br-PEG3-NH-Boc;N-Boc-PEG3-bromide;BocNH-PEG3-CH2CH2Br;Boc-NH-PEG4-bromide;Bocamine-PEG3-bromide;t-boc-N-amido-PEG4-bromide;1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE;N-Boc-2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethanamine;2-{2-[2-(2-Boc-aminoethoxy)ethoxy]ethoxy}ethyl Bromide
- CBNumber
- CB9648409
- Molecular Formula
- C13H26BrNO5
- Formula Weight
- 356.25
- MOL File
- Mol file
1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE Property
- Boiling point:
- 422.1±35.0 °C(Predicted)
- Density
- 1.238±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 12.23±0.46(Predicted)
- form
- Oil
- color
- Yellow
- InChI
- InChI=1S/C13H26BrNO5/c1-13(2,3)20-12(16)15-5-7-18-9-11-19-10-8-17-6-4-14/h4-11H2,1-3H3,(H,15,16)
- InChIKey
- GNDQONYTPMGMTM-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NCCOCCOCCOCCBr
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 262902
- Product name
- 1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide
- Packaging
- 25mg
- Price
- $496
- Updated
- 2021/12/16
- Product number
- B621210
- Product name
- 1-Boc-amino-3,6,9-trioxaundecanyl-11-bromide
- Packaging
- 500mg
- Price
- $1135
- Updated
- 2021/12/16
- Product number
- CHM0067174
- Product name
- 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $1732.5
- Updated
- 2021/12/16
- Product number
- CS-0068003
- Product name
- N-Boc-PEG4-bromide
- Purity
- ≥97.0%
- Packaging
- 1g
- Price
- $299
- Updated
- 2021/12/16
- Product number
- BIPG1666
- Product name
- N-Boc-PEG3-bromide
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE Chemical Properties,Usage,Production
Description
N-Boc-PEG3-bromide is a PEG linker containing a Boc protected amine and a bromide group. The protected amine can be deprotected under mild acidic conditions. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Chemical Properties
Yellow Oil
Uses
N-Boc-PEG4-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG4-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50
Cleavable Linker; PEGs; Alkyl/ether
References
[1] Jan Anderl, et al. Amatoxin-Conjugates with Improved Linkers. US20130259880A1
1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE manufacturers
- Product
- N-Boc-PEG4-bromide 1076199-21-7
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-06
- Product
- Br-PEG3-NHBoc 1076199-21-7
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-25
- Product
- 1-BOC-AMINO-3,6,9-TRIOXAUNDECANYL-11-BROMIDE 1076199-21-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19