Hydroxy-PEG3-t-butyl acetate
- Product Name
- Hydroxy-PEG3-t-butyl acetate
- CAS No.
- 518044-31-0
- Chemical Name
- Hydroxy-PEG3-t-butyl acetate
- Synonyms
- tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate;HO-PEG3-CH2COOtBu;OH-PEG3-CH2COOtBu;Hydroxy-PEG3-CH2-Boc;Hydroxy-PEG3-CH2COOtBu;Hydroxy-PEG3-CH2CO2tBu;Hydroxy-PEG3-t-butyl acetate;tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate(WXPC0085);Acetic acid, [2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethylester;Acetic acid, 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB43070428
- Molecular Formula
- C12H24O6
- Formula Weight
- 264.32
- MOL File
- 518044-31-0.mol
Hydroxy-PEG3-t-butyl acetate Property
- Boiling point:
- 351.2±27.0 °C(Predicted)
- Density
- 1.071±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 14.36±0.10(Predicted)
- form
- viscous liquid
- color
- Colourless
- InChI
- InChI=1S/C12H24O6/c1-12(2,3)18-11(14)10-17-9-8-16-7-6-15-5-4-13/h13H,4-10H2,1-3H3
- InChIKey
- YZXRUQCLSBHYHG-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)COCCOCCOCCO
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H952863
- Product name
- Hydroxy-Peg3-CH2CO2tBu
- Packaging
- 50mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- H952863
- Product name
- Hydroxy-Peg3-CH2CO2tBu
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- AS103955
- Product name
- HO-PEG3-CH2COOtBu
- Purity
- 95+%
- Packaging
- 1g
- Price
- $292
- Updated
- 2021/12/16
- Product number
- BP-22096
- Product name
- Hydroxy-PEG3-CH2CO2tBu
- Purity
- 95%
- Packaging
- 500mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- AS103955
- Product name
- HO-PEG3-CH2COOtBu
- Purity
- 95+%
- Packaging
- 5G
- Price
- $720
- Updated
- 2021/12/16
Hydroxy-PEG3-t-butyl acetate Chemical Properties,Usage,Production
Description
Hydroxy-PEG3-CH2CO2tBu is a PEG linker containing a hydroxyl group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Hydroxy-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Hydroxy-PEG3-t-butyl acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Hydroxy-PEG3-t-butyl acetate Suppliers
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View Lastest Price from Hydroxy-PEG3-t-butyl acetate manufacturers
- Product
- tert-butyl 2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)acetate 518044-31-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- Hydroxy-PEG3-CH2-Boc 518044-31-0
- Price
- US $22.00-88.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 50kg
- Release date
- 2025-06-25