2-(2-Methoxyethoxy)ethanamine
- Product Name
- 2-(2-Methoxyethoxy)ethanamine
- CAS No.
- 31576-51-9
- Chemical Name
- 2-(2-Methoxyethoxy)ethanamine
- Synonyms
- MeO-PEG2-NH2;m-PEG2-amine;NH2-PEG2-OME;MeO-EG(2)-NH2;Methyl-PEG2-amine;2-(2-Methoxyethoxy)ethanamine;2-(2-Methoxyethoxy)ethylamine;mPEG2-NH2;EthanaMine, 2-(2-Methoxyethoxy)-;2-(2-Methoxyethoxy)ethoxy]ethenamine
- CBNumber
- CB71510916
- Molecular Formula
- C5H13NO2
- Formula Weight
- 119.16
- MOL File
- 31576-51-9.mol
2-(2-Methoxyethoxy)ethanamine Property
- Boiling point:
- 163.7±15.0 °C(Predicted)
- Density
- 0.934±0.06 g/cm3(Predicted)
- refractive index
- n/D 1.429
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- pka
- 8.75±0.10(Predicted)
- form
- Solid
- color
- Colourless to Off-White
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3
- InChIKey
- QWCGXANSAOXRFE-UHFFFAOYSA-N
- SMILES
- C(N)COCCOC
Safety
- RIDADR
- 3265
- HazardClass
- 8
- PackingGroup
- Ⅱ
- HS Code
- 2922190090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 901159
- Product name
- 2-(2-Methoxyethoxy)ethanamine
- Purity
- ≥95%
- Packaging
- 5G
- Price
- $237
- Updated
- 2025/07/31
- Product number
- M262910
- Product name
- 2-(2-Methoxyethoxy)ethanamine
- Packaging
- 250mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-W008429
- Product name
- m-PEG2-Amine
- Purity
- >97.0%
- Packaging
- 50mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-W008429
- Product name
- m-PEG2-Amine
- Purity
- >97.0%
- Packaging
- 100mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- CS-W008429
- Product name
- m-PEG2-Amine
- Purity
- >97.0%
- Packaging
- 250mg
- Price
- $93
- Updated
- 2021/12/16
2-(2-Methoxyethoxy)ethanamine Chemical Properties,Usage,Production
Description
m-PEG2-amine is a PEG linker containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
2-(2-Methoxyethoxy)ethanamine is a reactant in the preparation of cyclopeptoids, a phase-transfer catalyst.
Synthesis
179820-15-6
31576-51-9
2.2.1.3 Synthesis of 2-(2-methoxyethoxy)ethylamine (2d) A mixture of N-[2-(2-methoxyethoxy)ethyl]phthalimide (2c) (27 mmol) and hydrazine monohydrate (43 mmol) in ethanol (30 mL) was refluxed for 3 hours at 100 °C. Upon completion of the reaction, the mixture was cooled to room temperature, filtered, and the filtrate was evaporated. Acetone (50 mL) was added to the residue and the precipitate was filtered. Subsequently, the filtrate was concentrated under reduced pressure to give an orange colored oil 2d in 62% yield. 1H NMR (500 MHz, CDCl3): δ 1.83 (s, 1H), 2.00 (s, 1H), 2.15 (s, 1H), 2.87 (t, J = 5.3 Hz, 1H), 3.35-3.39 (m, 2H), 3.41 (t, J = 6.4 Hz, 1H), 3.50 (t, J = 5.3 Hz, 1H) 3.52-3.55 (m, 2H), 3.60 (dd, J = 5.7, 3.3 Hz, 1H), 3.64 (dd, J = 5.6, 3.8 Hz, 1H), 3.73 (t, J = 6.5 Hz, 1H) ppm; HR ESI-MS (in MeOH): m/z [M + H]+ calcd. 120.0973, found 120.1047. found 120.1047.
IC 50
Cleavable Linker; PEGs
References
[1] Journal of Organic Chemistry, 2011, vol. 76, # 6, p. 1683 - 1691
[2] Journal of Organic Chemistry, 2010, vol. 75, # 3, p. 598 - 610
[3] Inorganica Chimica Acta, 2016, vol. 452, p. 159 - 169
[4] Patent: WO2009/109035, 2009, A1. Location in patent: Page/Page column 57-58
2-(2-Methoxyethoxy)ethanamine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2-Methoxyethoxy)ethanamine manufacturers
- Product
- 2-(2-methoxyethoxy)ethanamine 31576-51-9
- Price
- US $1629.00/g
- Min. Order
- 0.5g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-15
- Product
- m-PEG2-Amine 31576-51-9
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-06
- Product
- 2-(2-Methoxyethoxy)ethanamine 31576-51-9
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-20