2-(2-Methoxyethoxy)acetic acid
- Product Name
- 2-(2-Methoxyethoxy)acetic acid
- CAS No.
- 16024-56-9
- Chemical Name
- 2-(2-Methoxyethoxy)acetic acid
- Synonyms
- DOHA;TIMTEC-BB SBB008497;2-(2-Methoxyoxyacid;3,6-DIOXAHEPTANOIC ACID;2-(2-Methoxyethoxy)Acetic;(2-Methoxyethoxy)essigsure;(2-methoxyethoxy)acetic acid;2-(2-METHOXYETHOXY)ACETIC ACID;o-(2-methoxyethyl)glycolic acid;2-(2-methoxyethoxy)ethanoic acid
- CBNumber
- CB4434197
- Molecular Formula
- C5H10O4
- Formula Weight
- 134.13
- MOL File
- 16024-56-9.mol
2-(2-Methoxyethoxy)acetic acid Property
- Boiling point:
- 245-250 °C (lit.)
- Density
- 1.18 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.436(lit.)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Chloroform, DMSO, Methanol
- form
- Oil
- pka
- 3.40±0.10(Predicted)
- color
- Clear Colourless
- Water Solubility
- Fully miscible in water.
- BRN
- 1753567
- InChIKey
- CLLLODNOQBVIMS-UHFFFAOYSA-N
- CAS DataBase Reference
- 16024-56-9(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 1
- HazardClass
- 8
- PackingGroup
- II
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 407011
- Product name
- 2-(2-Methoxyethoxy)acetic acid
- Purity
- technical grade
- Packaging
- 250ml
- Price
- $357
- Updated
- 2025/07/31
- Product number
- 407011
- Product name
- 2-(2-Methoxyethoxy)acetic acid
- Purity
- technical grade
- Packaging
- 1l
- Price
- $933
- Updated
- 2023/06/20
- Product number
- M262785
- Product name
- 2-(2-Methoxyethoxy)aceticAcid(90%)
- Packaging
- 10g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- M262785
- Product name
- 2-(2-Methoxyethoxy)aceticAcid(90%)
- Packaging
- 100g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 143402
- Product name
- 2-(2-Methoxyethoxy)acetic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
2-(2-Methoxyethoxy)acetic acid Chemical Properties,Usage,Production
Chemical Properties
Colorless to pale yellow liquid
Uses
2-(2-Methoxyethoxy)acetic Acid is a urinary metabolite of Diglyme (D446300) that is a reproductive toxin. 2-(2-Methoxyethoxy)acetic Acid can be used as a biomarker of exposure for jet fuel JP-8 workers.
Synthesis
109-86-4
5292-43-3
16024-56-9
General procedure for the synthesis of methoxyethoxyacetic acid from 2-methoxyethanol and tert-butyl bromoacetate: 2-methoxyethanol (10 g, 131.4 mmol) and potassium tert-butoxide (17.67 g, 157.68 mmol) were dissolved in 100 mL of tetrahydrofuran (THF). The reaction mixture was heated to 45 °C, maintained for 1 h and then cooled to room temperature. To the above mixture was added tert-butyl bromoacetate (25.63 g, 131.41 mmol) and the reaction was stirred at room temperature for 16 hours. After completion of the reaction, the reaction mixture was concentrated and the residue was dissolved in water. The pH of the aqueous phase was adjusted to 12-12.5 with 1 M sodium hydroxide aqueous solution and stirring was continued for 12-14 hours at room temperature. Subsequently, the pH of the aqueous phase was adjusted with 10% aqueous phosphoric acid solution to 2. The product was extracted with dichloromethane (DCM). The DCM was removed by rotary evaporator to give 2-(2-methoxyethoxy)acetic acid as an oil (4.1 g, 23% yield).
References
[1] Patent: WO2015/79459, 2015, A1. Location in patent: Paragraph 00261
2-(2-Methoxyethoxy)acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2-Methoxyethoxy)acetic acid manufacturers
- Product
- 2-(2-Methoxyethoxy)acetic acid 16024-56-9
- Price
- US $0.00/G
- Min. Order
- 100G
- Purity
- 90%min
- Supply Ability
- 30KG/month
- Release date
- 2023-02-02
- Product
- 2-(2-Methoxyethoxy)acetic acid 16024-56-9
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-10