N3-PEG4-tBu
- Product Name
- N3-PEG4-tBu
- CAS No.
- 581066-04-8
- Chemical Name
- N3-PEG4-tBu
- Synonyms
- N3-PEG4-tBu;N3-PEG4-tBul;Azido-PEG4-Boc;Azido-PEG4-COOtBu;N3-PEG4-CH2CH2COOtBu;Azido-PEG4-tBu Ester;Azido-PEG4-tButly ester;Azido-PEG4-CH2CH2COOtBu;N3-?PEG4-?t-?butyl ester;Azido-PEG5-t-butyl ester
- CBNumber
- CB72546987
- Molecular Formula
- C15H29N3O6
- Formula Weight
- 347.40726
- MOL File
- 581066-04-8.mol
N3-PEG4-tBu Property
- refractive index
- 1.449 (589.3 nm 23℃)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS103966
- Product name
- N3-PEG4-CH2CH2COOtBu
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $258
- Updated
- 2021/12/16
- Product number
- BP-20436
- Product name
- Azido-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 1g
- Price
- $490
- Updated
- 2021/12/16
- Product number
- 280702
- Product name
- N3-PEG4-tBu
- Packaging
- 1g
- Price
- $493
- Updated
- 2021/12/16
- Product number
- AS103966
- Product name
- N3-PEG4-CH2CH2COOtBu
- Purity
- 95+%
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
- Product number
- BP-20436
- Product name
- Azido-PEG4-t-butylester
- Purity
- 98%
- Packaging
- 5G
- Price
- $1150
- Updated
- 2021/12/16
N3-PEG4-tBu Chemical Properties,Usage,Production
Description
Azido-PEG4-t-butyl ester is a click chemistry linker containing an azide (N3) and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive toward alkyne, BCN, DBCO via Click Chemistry . The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N3-PEG4-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
N3-PEG4-tBu Suppliers
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- +1 (888) 615-9178 / (561) 791-8787
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View Lastest Price from N3-PEG4-tBu manufacturers
- Product
- tert-butyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate 581066-04-8
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 581066-04-8
- Release date
- 2025-09-12
- Product
- azido-PEG4-t-Butyl ester 581066-04-8
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23