ChemicalBook > CAS DataBase List > N3-PEG4-tBu

N3-PEG4-tBu

Product Name: N3-PEG4-tBu
CAS No.: 581066-04-8
Chemical Name: N3-PEG4-tBu
Synonyms: N3-PEG4-tBu;N3-PEG4-tBul;Azido-PEG4-Boc;Azido-PEG4-COOtBu;N3-PEG4-CH2CH2COOtBu;Azido-PEG4-tBu Ester;Azido-PEG4-tButly ester;Azido-PEG4-CH2CH2COOtBu;N3-?PEG4-?t-?butyl ester;Azido-PEG5-t-butyl ester
CBNumber: CB72546987
Molecular Formula: C15H29N3O6
Formula Weight: 347.40726
MOL File: 581066-04-8.mol

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N3-PEG4-tBu Property

refractive index: 1.449 (589.3 nm 23℃)
storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-20436
Product name: Azido-PEG4-t-butylester
Purity: 98%
Packaging: 1g
Price: $490
Updated: 2021/12/16

ChemPep

Product number: 280702
Product name: N3-PEG4-tBu
Packaging: 1g
Price: $493
Updated: 2021/12/16

Activate Scientific

Product number: AS103966
Product name: N3-PEG4-CH2CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $532
Updated: 2021/12/16

BroadPharm

Product number: BP-20436
Product name: Azido-PEG4-t-butylester
Purity: 98%
Packaging: 5G
Price: $1150
Updated: 2021/12/16

chempep

Product number: 280702
Product name: N3-PEG4-tBu
Purity: >=95%
Packaging: 5g
Price: $1175
Updated: 2021/12/16

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N3-PEG4-tBu Chemical Properties,Usage,Production

Description

Azido-PEG4-t-butyl ester is a click chemistry linker containing an azide (N3) and a t-butyl ester moiety. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive toward alkyne, BCN, DBCO via Click Chemistry . The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Azido-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG4-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N3-PEG4-tBu manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: tert-butyl 1-azido-3,6,9,12-tetraoxapentadecan-15-oate 581066-04-8
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 581066-04-8
Release date: 2025-09-12

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG4-t-Butyl ester 581066-04-8
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-23

581066-04-8, N3-PEG4-tBuRelated Search:

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N3-PEG4-tBu

N3-PEG4-CH2CH2COOtBu

15-Azido-4,7,10,13-tetraoxapentadecanoic acid 1,1-dimethylethyl ester

N3-PEG4-CH2CH2COOtBu

Azido-PEG5-t-butyl ester

Azido-PEG4-COOtBu

N3-?PEG4-?t-?butyl ester

Azido-PEG4-Boc

Azido-PEG4-tButly ester

Azido-PEG4-tBu Ester

N3-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxapentadecanoic acid, 15-azido-, 1,1-dimethylethyl ester

N3-PEG4-tBul

Azido-PEG4-CH2CH2COOtBu

N3-PEG4-CH2CH2COOt<

581066-04-8

C15H29N3O6

SiChem

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