Bromo-PEG4-t-butyl ester

Product Name: Bromo-PEG4-t-butyl ester
CAS No.: 564476-32-0
Chemical Name: Bromo-PEG4-t-butyl ester
Synonyms: Br-PEG4-C2-Boc;Br-PEG4-COOtBu;CAS_564476-32-0;Br-PEG4-CH2CH2COOtBu;Br-PEG4-t-butyl ester;Bromo-PEG5-t-butyl ester;Bromo-PEG4-t-butyl ester;1,1-Dimethylethyl 15-bromo-4,7,10,13-tetraoxapentadecanoate;tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate;4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester
CBNumber: CB03048720
Molecular Formula: C15H29BrO6
Formula Weight: 385.29
MOL File: 564476-32-0.mol

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Bromo-PEG4-t-butyl ester Property

Boiling point:: 415.8±35.0 °C(Predicted)
Density: 1.210±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C15H29BrO6/c1-15(2,3)22-14(17)4-6-18-8-10-20-12-13-21-11-9-19-7-5-16/h4-13H2,1-3H3
InChIKey: WLKHUFASPMJBHB-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCBr

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0107159
Product name: Br-PEG4-C2-Boc
Packaging: 50mg
Price: $90
Updated: 2021/12/16

BroadPharm

Product number: BP-20711
Product name: Bromo-PEG4-t-butylester
Purity: 98%
Packaging: 500mg
Price: $140
Updated: 2021/12/16

ChemScene

Product number: CS-0107159
Product name: Br-PEG4-C2-Boc
Packaging: 100mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0107159
Product name: Br-PEG4-C2-Boc
Packaging: 250mg
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: 2640CT
Product name: Bromo-PEG4-t-butylester
Packaging: 100mg
Price: $522
Updated: 2021/12/16

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Bromo-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Bromo-PEG4-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Br-PEG4-C2-Boc is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Br-PEG4-C2-Boc is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize antibody drug conjugates (ADC).

target

Cleavable

PEGs

Alkyl/ether

IC 50

Cleavable Linker; PEGs; Alkyl/ether

References

[1] Robert Yongxin Zhao, et al. Cytotoxic agents. WO2003068144A2.

Bromo-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG4-t-butyl ester Suppliers

China 67 India 1 United Kingdom 1 United States 5 Global 74

Borenpharm Co., Ltd

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View Lastest Price from Bromo-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Br-PEG4-COOtBu 564476-32-0
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-25

564476-32-0, Bromo-PEG4-t-butyl esterRelated Search:

Tetraethyl decamethylenediphosphonate, 98% Bromo-PEG3-Acid Ethanol, 2-(2-bromoethoxy)- Bromo-PEG1-CH2CO2tBu Amino-PEG5-t-butyl ester H2N-PEG2-tBu H2N-PEG4-tBu Bromoacetic acid Methyl bromoacetate tert-Butyl acetate tert-Butyl 2-bromo-2-methylpropanoate Phosphorus tribromide Br-PEG5-acid Bromo-PEG3-t-butyl ester Bromo-PEG5-t-butyl ester Bromo-PEG6-t-butyl ester Bromo-PEG4-acid Bromo-PEG2-acid

CAS_564476-32-0

Bromo-PEG4-t-butyl ester

Bromo-PEG5-t-butyl ester

Br-PEG4-t-butyl ester

Br-PEG4-CH2CH2COOtBu

Br-PEG4-COOtBu

Br-PEG4-C2-Boc

4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester

3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-bromo-, 1,1-dimethylethylester

Br-PEG4-CH2CH2COOtBu/4,7,10,13-Tetraoxapentadecanoic acid, 15-bromo-, 1,1-dimethylethyl ester

tert-butyl 3-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]propanoate

1,1-Dimethylethyl 15-bromo-4,7,10,13-tetraoxapentadecanoate

564476-32-0

C15H29BrO6