Br-PEG5-acid
- Product Name
- Br-PEG5-acid
- CAS No.
- 1817735-27-5
- Chemical Name
- Br-PEG5-acid
- Synonyms
- Br-PEG5-acid;Bromo-PEG5-C2-acid;Br-PEG5-CH2CH2COOH;Bromo-PEG5-propionic acid;1-Bromo-3,6,9,12,15-pentaoxaoctadecan-18-oic acid;Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;Br-PEG5-CH2CH2COOH/Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
- CBNumber
- CB93303329
- Molecular Formula
- C13H25BrO7
- Formula Weight
- 373.24
- MOL File
- 1817735-27-5.mol
Br-PEG5-acid Property
- Boiling point:
- 462.1±45.0 °C(Predicted)
- Density
- 1.320±0.06 g/cm3(Predicted)
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P331Do NOT induce vomiting.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS107895
- Product name
- Br-PEG5-CH2CH2COOH
- Purity
- 97%
- Packaging
- 1g
- Price
- $618
- Updated
- 2021/12/16
- Product number
- BP-22878
- Product name
- Bromo-PEG5-acid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $620
- Updated
- 2021/12/16
- Product number
- BP-22878
- Product name
- Bromo-PEG5-acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $980
- Updated
- 2021/12/16
- Product number
- B-1497
- Product name
- Br-PEG5-CH2CH2COOH
- Purity
- 97%
- Packaging
- 1g
- Price
- $440
- Updated
- 2021/12/16
Br-PEG5-acid Chemical Properties,Usage,Production
Description
Bromo-PEG5-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Br-PEG5-acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Br-PEG5-acid manufacturers
- Product
- Br-PEG5-acid 1817735-27-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25