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Br-PEG5-acid

Product Name
Br-PEG5-acid
CAS No.
1817735-27-5
Chemical Name
Br-PEG5-acid
Synonyms
Br-PEG5-acid;Bromo-PEG5-C2-acid;Br-PEG5-CH2CH2COOH;Bromo-PEG5-propionic acid;1-Bromo-3,6,9,12,15-pentaoxaoctadecan-18-oic acid;Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;Br-PEG5-CH2CH2COOH/Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
CBNumber
CB93303329
Molecular Formula
C13H25BrO7
Formula Weight
373.24
MOL File
1817735-27-5.mol
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Br-PEG5-acid Property

Boiling point:
462.1±45.0 °C(Predicted)
Density 
1.320±0.06 g/cm3(Predicted)
pka
4.28±0.10(Predicted)
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P331Do NOT induce vomiting.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS107895
Product name
Br-PEG5-CH2CH2COOH
Purity
97%
Packaging
1g
Price
$618
Updated
2021/12/16
BroadPharm
Product number
BP-22878
Product name
Bromo-PEG5-acid
Purity
98%
Packaging
500mg
Price
$620
Updated
2021/12/16
BroadPharm
Product number
BP-22878
Product name
Bromo-PEG5-acid
Purity
98%
Packaging
1g
Price
$980
Updated
2021/12/16
Acrotein
Product number
B-1497
Product name
Br-PEG5-CH2CH2COOH
Purity
97%
Packaging
1g
Price
$440
Updated
2021/12/16
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Br-PEG5-acid Chemical Properties,Usage,Production

Description

Bromo-PEG5-acid is a PEG linker containing a bromide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bromo-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Br-PEG5-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Br-PEG5-acid Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Nanjing Junnahe Biopharmaceutical Co., Ltd
Tel
025-58367986 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
354
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Aikon International Limited
Tel
025-58859352 19370895928
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15082
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
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View Lastest Price from Br-PEG5-acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG5-acid 1817735-27-5
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-25

1817735-27-5, Br-PEG5-acidRelated Search:


  • Br-PEG5-acid
  • Bromo-PEG5-propionic acid
  • Br-PEG5-CH2CH2COOH
  • Bromo-PEG5-C2-acid
  • Br-PEG5-CH2CH2COOH/Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • Propanoic acid, 3-[(14-bromo-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • 1-Bromo-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • 1817735-27-5