Bromo-PEG6-azide
- Product Name
- Bromo-PEG6-azide
- CAS No.
- 2062663-64-1
- Chemical Name
- Bromo-PEG6-azide
- Synonyms
- Br-PEG6-N3;Azido-PEG6-Br;Bro-PEG7-azido;N3-PEG6-CH2CH2Br;Bromo-PEG6-azide;1-?Azido-?20-?bromo-?3,?6,?9,?12,?15,?18-?hexaoxaicosane;N3-PEG6-CH2CH2Br/3,6,9,12,15,18-Hexaoxaeicosane, 1-azido-20-bromo-
- CBNumber
- CB73311647
- Molecular Formula
- C14H29BrN3O6+
- Formula Weight
- 415.30056
- MOL File
- 2062663-64-1.mol
Bromo-PEG6-azide Property
- storage temp.
- 2-8°C, protect from light
- form
- Oil
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-23443
- Product name
- Bromo-PEG6-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- BP-23443
- Product name
- Bromo-PEG6-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- BP-23443
- Product name
- Bromo-PEG6-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $720
- Updated
- 2021/12/16
- Product number
- AS107838
- Product name
- N3-PEG6-CH2CH2Br
- Purity
- 97%
- Packaging
- 1g
- Price
- $869
- Updated
- 2021/12/16
- Product number
- B-1433
- Product name
- N3-PEG6-CH2CH2Br
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $260.33
- Updated
- 2021/12/16
Bromo-PEG6-azide Chemical Properties,Usage,Production
Description
Bromo-PEG6-azide consist of a bromide(Br), a terminal azide(N3) and a PEG6 spacer. PEG spacer increases solubility in aqueous media. The bromide (Br) is a good leaving group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
Uses
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG6-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG6-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG6-azide Suppliers
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View Lastest Price from Bromo-PEG6-azide manufacturers
- Product
- N3-PEG6-Br 2062663-64-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-04
- Product
- Azido-PEG6-Br 2062663-64-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23