Bromo-PEG3-azide
- Product Name
- Bromo-PEG3-azide
- CAS No.
- 1446282-43-4
- Chemical Name
- Bromo-PEG3-azide
- Synonyms
- Br-PEG3-N3;N3-PEG3-Br;Azido-PEG3-Br;N3-PEG3-CH2CH2Br;Bromo-PEG4-azide;Bromo-PEG3-azide;1-Azido-2-(2-[2-(2-bromoethoxy)ethoxy]ethoxy)ethane;N3-PEG3-CH2CH2Br/Ethane, 1-(2-azidoethoxy)-2-[2-(2-bromoethoxy)ethoxy]-
- CBNumber
- CB93062444
- Molecular Formula
- C8H17BrN3O3+
- Formula Weight
- 283.14288
- MOL File
- 1446282-43-4.mol
Bromo-PEG3-azide Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- clear liquid
- color
- Colorless to Light orange to Yellow
Safety
- HS Code
- 2929.90.5090
N-Bromosuccinimide Price
- Product number
- B6081
- Product name
- Bromo-PEG3-Azide
- Packaging
- 250MG
- Price
- $515
- Updated
- 2025/07/31
- Product number
- B750713
- Product name
- Bromo-PEG3-azide
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-21718
- Product name
- Bromo-PEG3-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- 0448DY
- Product name
- Bromo-PEG3-azide
- Packaging
- 250mg
- Price
- $811
- Updated
- 2021/12/16
- Product number
- B-0642
- Product name
- N3-PEG3-CH2CH2Br
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $302.5
- Updated
- 2021/12/16
Bromo-PEG3-azide Chemical Properties,Usage,Production
Description
Bromo-PEG3-azide is a PEG linker containing a bromide group and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions.
Uses
Bromo-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG3-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG3-azide Suppliers
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View Lastest Price from Bromo-PEG3-azide manufacturers
- Product
- Azido-PEG3-Br 1446282-43-4
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23