2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL

Product Name: 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
CAS No.: 86520-52-7
Chemical Name: 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
Synonyms: N3-PEG3-OH;Azido-PEG3;azido-PEG3-OH;Azide-PEG3-OH;Azido-PEG3-alcohol;AZIDO-PEG3-HYDROXY;8-Azido-3,6-dioxaoctanol;8-Azido-3,6-dioxa-1-octanol;Azido-PEG3-alcohol,N3-PEG3-OH;1-Azido-8-hydroxy-3,6-dioxaoctane
CBNumber: CB5648133
Molecular Formula: C6H13N3O3
Formula Weight: 175.18572
MOL File: Mol file

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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Property

Flash point:: -33℃
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Oil
color: Colourless to Light Yellow
Appearance: colorless liquid
BRN: 4418543
InChI: InChI=1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2
InChIKey: PMNIHDBMMDOUPD-UHFFFAOYSA-N
SMILES: C(O)COCCOCCN=[N+]=[N-]

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-38
Safety Statements: 16
RIDADR: UN 2398 3 / PGII
WGK Germany: 3
HS Code: 2929900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 727423
Product name: 2-[2-(2-Azidoethoxy)ethoxy]ethanol solution
Purity: ~0.5M in
Packaging: 10ml
Price: $316
Updated: 2025/07/31

TCI Chemical

Product number: A2297
Product name: 2-[2-(2-Azidoethoxy)ethoxy]ethan-1-ol
Purity: min. 95.0 %
Packaging: 200MG
Price: $95
Updated: 2025/07/31

TCI Chemical

Product number: A2297
Product name: 2-[2-(2-Azidoethoxy)ethoxy]ethan-1-ol
Purity: min. 95.0 %
Packaging: 1G
Price: $285
Updated: 2025/07/31

TRC

Product number: A848550
Product name: 2-[2-(2-Azidoethoxy)ethoxy]ethanol
Packaging: 5g
Price: $205
Updated: 2021/12/16

AK Scientific

Product number: AMTGC412
Product name: Azido-PEG3-alcohol
Packaging: 5g
Price: $210
Updated: 2021/12/16

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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Chemical Properties,Usage,Production

Description

Azido-PEG3-alcohol is a click chemistry PEG linker containing an azide group and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Chemical Properties

Yellowish Liquid

Uses

Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG3-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

PEGs

References

[1] Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. DOI:10.1016/j.bmc.2019.115228

2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Suppliers

Canada 2 China 149 Germany 1 India 5 United Kingdom 1 United States 8 Global 166

Dipag (Weinan) Biotechnology Co., Ltd

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View Lastest Price from 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: 2-(2-(2-azidoethoxy)ethoxy)ethan-1-ol 86520-52-7
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 86520-52-7
Release date: 2025-09-12

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: Azido-PEG3-alcohol 86520-52-7
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD

Product: 2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol 86520-52-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000 kgs
Release date: 2024-05-20

86520-52-7, 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOLRelated Search:

N3-PEG4-tBu Azido-PEG12-NHS ester Azido-PEG8-NHS ester Azido-PEG2-acid Azide-PEG5-t-butyl ester Azido-PEG2-t-butyl ester Azido-PEG5-NHS ester Azido-dPEG4-acid N3-PEG3-tBu Azido-PEG12-t-butyl ester N3-PEG6-tBu 1-AZIDO-3,6,9-TRIOXAUNDECANE-11-OL 1-Azidohexaethylene Glycol 3,6,9,12,15,18,21,24-Octaoxapentacosan-1-amine MPEG8-N3 Azido-PEG6 AMINO-PEG12-T-BUTYL ESTER 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL

2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL

azido-PEG3-OH

Ethanol, 2-[2-(2-azidoethoxy)ethoxy]-

2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol

1-Azido-8-hydroxy-3,6-dioxaoctane

8-Azido-3,6-dioxaoctanol

2-[2-(2-Azidoethoxy)ethoxy]ethanol solution

8-Azido-3,6-dioxaoctanol solution

Azido-PEG3

Azido-PEG3-alcohol

N3-PEG3-OH

AZIDO-PEG3-HYDROXY

Azido-PEG3-alcohol,N3-PEG3-OH

Azide-PEG3-OH

8-Azido-3,6-dioxa-1-octanol

2-[2-(2-Azidoethoxy)ethoxy]ethanol - [A73318]

86520-52-7

Nitric Oxide Reagents

Cross Linking Reagents

building block

peg