ChemicalBook > CAS DataBase List > 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL

2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL

Product Name
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
CAS No.
86520-52-7
Chemical Name
2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
Synonyms
N3-PEG3-OH;Azido-PEG3;azido-PEG3-OH;Azide-PEG3-OH;Azido-PEG3-alcohol;AZIDO-PEG3-HYDROXY;8-Azido-3,6-dioxaoctanol;8-Azido-3,6-dioxa-1-octanol;Azido-PEG3-alcohol,N3-PEG3-OH;1-Azido-8-hydroxy-3,6-dioxaoctane
CBNumber
CB5648133
Molecular Formula
C6H13N3O3
Formula Weight
175.18572
MOL File
Mol file
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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Property

Flash point:
-33℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Oil
color 
Colourless to Light Yellow
Appearance
colorless liquid
BRN 
4418543
InChI
InChI=1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2
InChIKey
PMNIHDBMMDOUPD-UHFFFAOYSA-N
SMILES
C(O)COCCOCCN=[N+]=[N-]
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-38
Safety Statements 
16
RIDADR 
UN 2398 3 / PGII
WGK Germany 
3
HS Code 
2929900090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
727423
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethanol solution
Purity
~0.5M in
Packaging
10ml
Price
$316
Updated
2025/07/31
TCI Chemical
Product number
A2297
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethan-1-ol
Purity
min. 95.0 %
Packaging
200MG
Price
$95
Updated
2025/07/31
TCI Chemical
Product number
A2297
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethan-1-ol
Purity
min. 95.0 %
Packaging
1G
Price
$285
Updated
2025/07/31
TRC
Product number
A848550
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethanol
Packaging
5g
Price
$205
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA18102
Product name
2-[2-(2-Azidoethoxy)ethoxy]ethanol
Packaging
500mg
Price
$65
Updated
2021/12/16
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2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Chemical Properties,Usage,Production

Description

Azido-PEG3-alcohol is a click chemistry PEG linker containing an azide group and a terminal hydroxyl group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Chemical Properties

Yellowish Liquid

Uses

Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Azido-PEG3-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

reaction suitability

reaction type: click chemistry
reagent type: linker

IC 50

PEGs

References

[1] Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228. DOI:10.1016/j.bmc.2019.115228

2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2-(2-(2-azidoethoxy)ethoxy)ethan-1-ol 86520-52-7
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
86520-52-7
Release date
2025-09-12
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Azido-PEG3-alcohol 86520-52-7
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-06
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
Product
2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol 86520-52-7
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000 kgs
Release date
2024-05-20

86520-52-7, 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOLRelated Search:


  • 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL
  • azido-PEG3-OH
  • Ethanol, 2-[2-(2-azidoethoxy)ethoxy]-
  • 2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol
  • 1-Azido-8-hydroxy-3,6-dioxaoctane
  • 8-Azido-3,6-dioxaoctanol
  • 2-[2-(2-Azidoethoxy)ethoxy]ethanol solution
  • 8-Azido-3,6-dioxaoctanol solution
  • Azido-PEG3
  • Azido-PEG3-alcohol
  • N3-PEG3-OH
  • AZIDO-PEG3-HYDROXY
  • Azido-PEG3-alcohol,N3-PEG3-OH
  • Azide-PEG3-OH
  • 8-Azido-3,6-dioxa-1-octanol
  • 2-[2-(2-Azidoethoxy)ethoxy]ethanol - [A73318]
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