ChemicalBook > CAS DataBase List > Azido-PEG5-NHS ester

Azido-PEG5-NHS ester

Product Name
Azido-PEG5-NHS ester
CAS No.
1433996-86-1
Chemical Name
Azido-PEG5-NHS ester
Synonyms
N3-PEG5-SPA;N3-PEG5-NHS;AZIDO-PEG5-NHS;Azido-PEG5-NHS eater;N3-PEG5-CH2CH2COONHS;Azido-PEG5-NHS ester;Azido-PEG5-NHS Ester,N3-PEG5-NHS;2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate;N3-PEG5-CH2CH2COONHS/Propanoic acid, 3-[(14-azido-3,6,9,12-tetraoxatetradec-1-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB23062364
Molecular Formula
C17H28N4O9
Formula Weight
432.43
MOL File
1433996-86-1.mol
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Azido-PEG5-NHS ester Property

storage temp. 
Storage temp. -20°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
POL0002368
Product name
AZIDO-PEG5-NHS ESTER
Purity
95.00%
Packaging
5MG
Price
$498.96
Updated
2021/12/16
Apolloscientific
Product number
BIPG1157
Product name
Azido-PEG5-NHS ester
Packaging
100mg
Price
$546
Updated
2021/12/16
Activate Scientific
Product number
AS107846
Product name
N3-PEG5-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$790
Updated
2021/12/16
Acrotein
Product number
B-1446
Product name
N3-PEG5-CH2CH2COONHS
Purity
97%
Packaging
0.25g
Price
$247.5
Updated
2021/12/16
Acrotein
Product number
B-1446
Product name
N3-PEG5-CH2CH2COONHS
Purity
97%
Packaging
1g
Price
$550
Updated
2021/12/16
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Azido-PEG5-NHS ester Chemical Properties,Usage,Production

Description

Azido-PEG5-NHS ester is a click chemistry PEG reagent. The azide (N3) group can react with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG5-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG5-NHS ester Suppliers

Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3827
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10028
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
3983243027@qq.com
Country
China
ProdList
9797
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
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View Lastest Price from Azido-PEG5-NHS ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
N3-PEG5-NHS 1433996-86-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-03
Xian confluore Biological Technology Co., Ltd.
Product
azido-PEG5-NHS ester 1433996-86-1
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-23

1433996-86-1, Azido-PEG5-NHS esterRelated Search:


  • Azido-PEG5-NHS ester
  • AZIDO-PEG5-NHS
  • N3-PEG5-NHS
  • N3-PEG5-CH2CH2COONHS
  • Azido-PEG5-NHS Ester,N3-PEG5-NHS
  • N3-PEG5-SPA
  • 2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate
  • N3-PEG5-CH2CH2COONHS/Propanoic acid, 3-[(14-azido-3,6,9,12-tetraoxatetradec-1-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
  • Azido-PEG5-NHS eater
  • 1433996-86-1
  • peg