ChemicalBook > CAS DataBase List > Azido-PEG5-NHS ester
Azido-PEG5-NHS ester
- Product Name
- Azido-PEG5-NHS ester
- CAS No.
- 1433996-86-1
- Chemical Name
- Azido-PEG5-NHS ester
- Synonyms
- N3-PEG5-SPA;N3-PEG5-NHS;AZIDO-PEG5-NHS;Azido-PEG5-NHS eater;N3-PEG5-CH2CH2COONHS;Azido-PEG5-NHS ester;Azido-PEG5-NHS Ester,N3-PEG5-NHS;2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15-pentaoxaoctadecan-18-oate;N3-PEG5-CH2CH2COONHS/Propanoic acid, 3-[(14-azido-3,6,9,12-tetraoxatetradec-1-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB23062364
- Molecular Formula
- C17H28N4O9
- Formula Weight
- 432.43
- MOL File
- 1433996-86-1.mol
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Azido-PEG5-NHS ester Property
- storage temp.
- Storage temp. -20°C
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- POL0002368
- Product name
- AZIDO-PEG5-NHS ESTER
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.96
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1157
- Product name
- Azido-PEG5-NHS ester
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
Activate Scientific
- Product number
- AS107846
- Product name
- N3-PEG5-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $790
- Updated
- 2021/12/16
Acrotein
- Product number
- B-1446
- Product name
- N3-PEG5-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $247.5
- Updated
- 2021/12/16
Acrotein
- Product number
- B-1446
- Product name
- N3-PEG5-CH2CH2COONHS
- Purity
- 97%
- Packaging
- 1g
- Price
- $550
- Updated
- 2021/12/16
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Azido-PEG5-NHS ester Chemical Properties,Usage,Production
Description
Azido-PEG5-NHS ester is a click chemistry PEG reagent. The azide (N3) group can react with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Azido-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG5-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG5-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Azido-PEG5-NHS ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- azido-PEG5-NHS ester 1433996-86-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23
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