Azido-PEG6-NHS ester

Product Name: Azido-PEG6-NHS ester
CAS No.: 2055014-64-5
Chemical Name: Azido-PEG6-NHS ester
Synonyms: CAS_2055014-64-5;Azido-PEG6-NHS eater;N3-PEG6-CH2CH2COONHS;Azido-PEG6-NHS ester;Azido-PEG6-NHS ester,N3-PEG6-NHS;2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate;N3-PEG6-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-azido-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB43162882
Molecular Formula: C19H32N4O10
Formula Weight: 476.48
MOL File: 2055014-64-5.mol

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Azido-PEG6-NHS ester Property

storage temp.: Storage temp. -20°C
solubility: Soluble in Water, DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow
Appearance: pale yellow liquid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: POL0002371
Product name: AZIDO-PEG6-NHS ESTER
Purity: 95.00%
Packaging: 5MG
Price: $501.79
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1158
Product name: Azido-PEG6-NHS ester
Packaging: 100mg
Price: $546
Updated: 2021/12/16

BroadPharm

Product number: BP-21506
Product name: Azido-PEG6-NHSester
Purity: 98%
Packaging: 1g
Price: $600
Updated: 2021/12/16

Activate Scientific

Product number: AS107818
Product name: N3-PEG6-CH2CH2COONHS
Purity: 97%
Packaging: 1g
Price: $969
Updated: 2021/12/16

purepeg

Product number: 436906
Product name: N3-PEG6-CH2CH2COONHSEster
Purity: min.97%
Packaging: 500mg
Price: $260
Updated: 2021/12/16

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Azido-PEG6-NHS ester Chemical Properties,Usage,Production

Description

Azido-PEG6-NHS ester consist of an azide(N3) and an NHS ester function group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Azido-PEG6-NHS ester is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG6-NHS ester is also a PEG- and Alkyl/ether based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG6-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether; Cleavable Linker

References

[1] Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717. DOI:10.1002/anie.201709532
[2] John W. Babich, et al. Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies. WO2018187631A1.

Azido-PEG6-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG6-NHS ester Suppliers

China 47 United Kingdom 1 United States 3 Global 51

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
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ProdList: 9895
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3935
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Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
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Jinan elephant international trading co., LTD

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Country: China
ProdList: 6355
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828
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Email: info@amateksci.com
Country: China
ProdList: 28785
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Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
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Country: China
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SHANGHAI FDC-CHEMICAL CO.,LTD

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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
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Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
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Country: China
ProdList: 10267
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View Lastest Price from Azido-PEG6-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG6-NHS ester 2055014-64-5
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

2055014-64-5, Azido-PEG6-NHS esterRelated Search:

Azido-PEG6-azide Bromo-PEG6-azide BocNH-PEG6-CH2CH2N3 N3-PEG6-Hydrazide Azido-PEG6 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine Azide-PEG6-Tos Azido-PEG7-acid N3-PEG6-tBu Ethyl acetate Polyethylene Glycol

N3-PEG6-CH2CH2COONHS

CAS_2055014-64-5

Azido-PEG6-NHS ester

Azido-PEG6-NHS ester,N3-PEG6-NHS

N3-PEG6-CH2CH2COONHS/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-azido-, 2,5-dioxo-1-pyrrolidinyl ester

2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18-hexaoxahenicosan-21-oate

Azido-PEG6-NHS eater

2055014-64-5