Azide-PEG6-Tos
- Product Name
- Azide-PEG6-Tos
- CAS No.
- 906007-10-1
- Chemical Name
- Azide-PEG6-Tos
- Synonyms
- N3-PEG6-Tos;N3-PEG6-OTos;Azide-PEG6-Tos;Azido-PEG6-Tos;Azido-PEG6-OTs;17-Azido-3,6,9,12,15-pentaoxaheptadecyl 4-methylbenzenesulfonate;2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]- ethyl p-tosylate;N3-PEG6-Tos/3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-azido-, 1-(4-methylbenzenesulfonate)
- CBNumber
- CB13162856
- Molecular Formula
- C19H31N3O8S
- Formula Weight
- 461.53
- MOL File
- 906007-10-1.mol
Azide-PEG6-Tos Property
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AS107854
- Product name
- N3-PEG6-Tos
- Purity
- 97%
- Packaging
- 250mg
- Price
- $381
- Updated
- 2021/12/16
- Product number
- BP-23177
- Product name
- Azide-PEG6-Tos
- Purity
- 98%
- Packaging
- 1g
- Price
- $950
- Updated
- 2021/12/16
- Product number
- B-1424
- Product name
- N3-PEG6-Tos
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $366.67
- Updated
- 2021/12/16
Azide-PEG6-Tos Chemical Properties,Usage,Production
Description
Azide-PEG6-Tos consist of an azide group and a tosyl group. 6 PEG units increases solubility in aqueous media. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
Uses
Azide-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG6-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azide-PEG6-Tos Preparation Products And Raw materials
Raw materials
Preparation Products
Azide-PEG6-Tos Suppliers
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39999
- Advantage
- 60
- Tel
- 0431-80534353 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3827
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 86249
- Advantage
- 60
- Tel
- Fax
- -
- 13006575422@163.com
- Country
- China
- ProdList
- 6355
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28772
- Advantage
- 58
- Tel
- 021-61469567 13482353728
- Fax
- 021-61161605
- sales@fdc-chemical.com
- Country
- China
- ProdList
- 9964
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
- 1951
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32467
- Advantage
- 58
View Lastest Price from Azide-PEG6-Tos manufacturers
- Product
- N3-PEG6-Tos 906007-10-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-04
- Product
- Azido-PEG6-Tos 906007-10-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23