Azide-PEG6-Tos
- Product Name
- Azide-PEG6-Tos
- CAS No.
- 906007-10-1
- Chemical Name
- Azide-PEG6-Tos
- Synonyms
- N3-PEG6-Tos;N3-PEG6-OTos;Azide-PEG6-Tos;Azido-PEG6-Tos;Azido-PEG6-OTs;2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]- ethyl p-tosylate;N3-PEG6-Tos/3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-azido-, 1-(4-methylbenzenesulfonate)
- CBNumber
- CB13162856
- Molecular Formula
- C19H31N3O8S
- Formula Weight
- 461.53
- MOL File
- 906007-10-1.mol
Azide-PEG6-Tos Property
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- AS107854
- Product name
- N3-PEG6-Tos
- Purity
- 97%
- Packaging
- 250mg
- Price
- $381
- Updated
- 2021/12/16
- Product number
- BP-23177
- Product name
- Azide-PEG6-Tos
- Purity
- 98%
- Packaging
- 1g
- Price
- $950
- Updated
- 2021/12/16
- Product number
- B-1424
- Product name
- N3-PEG6-Tos
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $366.67
- Updated
- 2021/12/16
Azide-PEG6-Tos Chemical Properties,Usage,Production
Description
Azide-PEG6-Tos consist of an azide group and a tosyl group. 6 PEG units increases solubility in aqueous media. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.
Uses
Azide-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG6-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azide-PEG6-Tos Preparation Products And Raw materials
Raw materials
Preparation Products
Azide-PEG6-Tos Suppliers
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- 0431-0431-80514535 19917294565
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- China
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- United States
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- China
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- 13892832556
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- China
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View Lastest Price from Azide-PEG6-Tos manufacturers
- Product
- Azido-PEG6-Tos 906007-10-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23