Azide-PEG6-Tos

Product Name: Azide-PEG6-Tos
CAS No.: 906007-10-1
Chemical Name: Azide-PEG6-Tos
Synonyms: N3-PEG6-Tos;N3-PEG6-OTos;Azide-PEG6-Tos;Azido-PEG6-Tos;Azido-PEG6-OTs;2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]- ethyl p-tosylate;N3-PEG6-Tos/3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-azido-, 1-(4-methylbenzenesulfonate)
CBNumber: CB13162856
Molecular Formula: C19H31N3O8S
Formula Weight: 461.53
MOL File: 906007-10-1.mol

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Azide-PEG6-Tos Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS107854
Product name: N3-PEG6-Tos
Purity: 97%
Packaging: 250mg
Price: $381
Updated: 2021/12/16

BroadPharm

Product number: BP-23177
Product name: Azide-PEG6-Tos
Purity: 98%
Packaging: 1g
Price: $950
Updated: 2021/12/16

Acrotein

Product number: B-1424
Product name: N3-PEG6-Tos
Purity: 97%
Packaging: 0.5g
Price: $366.67
Updated: 2021/12/16

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Azide-PEG6-Tos Chemical Properties,Usage,Production

Description

Azide-PEG6-Tos consist of an azide group and a tosyl group. 6 PEG units increases solubility in aqueous media. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions.

Uses

Azide-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG6-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azide-PEG6-Tos Preparation Products And Raw materials

Raw materials

Preparation Products

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Azide-PEG6-Tos Suppliers

China 28 United States 3 Global 31

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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View Lastest Price from Azide-PEG6-Tos manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG6-Tos 906007-10-1
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

906007-10-1, Azide-PEG6-TosRelated Search:

Azido-PEG6-azide Bromo-PEG6-azide BocNH-PEG6-CH2CH2N3 N3-PEG6-Hydrazide Azido-PEG6-NHS ester Azido-PEG6 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine Azido-PEG7-acid N3-PEG6-tBu

Azide-PEG6-Tos

N3-PEG6-Tos

2[-2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]- ethyl p-tosylate

Azido-PEG6-OTs

Azido-PEG6-Tos

N3-PEG6-Tos/3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-azido-, 1-(4-methylbenzenesulfonate)

N3-PEG6-OTos

906007-10-1

C19H31N3O8S