Bromo-PEG1-azide
- Product Name
- Bromo-PEG1-azide
- CAS No.
- 1144106-65-9
- Chemical Name
- Bromo-PEG1-azide
- Synonyms
- Bromo-PEG1-azide;Bromo-PEG1-C2-azide;Bromo-PEG1-azide, Bromo-PEG1-N3;1-azido-2-(2-bromoethoxy)ethane;1-Azido-2-(2-bromoethoxy)ethane/Bromo-PEG1-C2-azide;inhibit,PROTAC Linkers,Bromo-PEG-1-C2-azide,BromoPEG1C2azide,Inhibitor,Bromo PEG1 C2 azide
- CBNumber
- CB64849564
- Molecular Formula
- C4H8BrN3O
- Formula Weight
- 194.03
- MOL File
- 1144106-65-9.mol
Bromo-PEG1-azide Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-24132
- Product name
- Bromo-PEG1-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $650
- Updated
- 2021/12/16
Bromo-PEG1-azide Chemical Properties,Usage,Production
Description
Bromo-PEG1-azide is a bifunctional PEG linker with a bromide (Br)group and an azide(N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions.
Uses
Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG1-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG1-azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Bromo-PEG1-azide manufacturers
- Product
- Azido-PEG1-Br 1144106-65-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23